Sökning: "Extracellular"
Visar resultat 16 - 20 av 1515 avhandlingar innehållade ordet Extracellular.
16. Remodelling of extracellular matrix in rectal cancer and preoperative radiotherapy
Sammanfattning : BACKGROUND Preoperative radiotherapy reduces local recurrence due to rectal cancer, but increases postoperative morbidity. The aim of this thesis was to study the impact of radiotherapy on extracellular matrix (ECM) remodelling enzymes and growth factors after radiotherapy and also their possible use as surrogate markers for complications. LÄS MER
17. Therapeutic potential of extracellular vesicles
Sammanfattning : Extracellular vesicles (EVs) are nanometer-sized, lipid membrane enclosed, vesicles that are secreted by most, if not all, cells and contain macromolecular material of the source cell including lipids, proteins and various nucleic acid species. Over the last two decades, EVs have been recognized as important mediators of cell-to-cell communication that influence both physiological and pathological conditions. LÄS MER
18. Extracellular matrix in atherosclerotic plaques: its role in plaque stability
Sammanfattning : Atherosclerosis is a systemic disease affecting the large arteries caused by the accumulation of lipids in the vessel wall. Cardiovascular disease due to atherosclerosis is today the most common cause of death globally through its end consequences: myocardial infarctions and stroke. LÄS MER
19. Non-coding RNAs and Extracellular Vesicles in Cutaneous Squamous Cell Carcinoma
Sammanfattning : Cutaneous squamous cell carcinoma (cSCC) ranks among the most widespread malignancies with metastatic potential. Investigating the molecular mechanism of tumorigenesis will enhance our understanding of cSCC. Aberrant expression of non-coding RNAs has been extensively reported in human cancers. LÄS MER
20. Regulation of cellular plasticity and extracellular vesicle secretion in breast cancer
Sammanfattning : Epithelial-to-mesenchymal transition (EMT) is a dynamic process controlling the transition of cells between epithelial and mesenchymal states in various physiological or pathological conditions. In cancer, EMT promotes cell dissemination and metastatic colonization, enriches tumors with stem cell populations and confers resistance to anticancer therapy. LÄS MER