Sökning: "Experimental sepsis"

Visar resultat 1 - 5 av 50 avhandlingar innehållade orden Experimental sepsis.

1. 1. Nitric oxide in experimental sepsis

   Författare :Peter Dahm; Anestesiologi och intensivvård; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intensive care; Nitric oxide; Sepsis; NO inhalation; Endotoxin; Acute lung injury; ARDS; Nitric oxide synthase; L-NMMA; L-NAME; Anestesiologi; Anaesthesiology; Pigs; intensivvård;

   Sammanfattning : Nitric oxide (NO) is important in the control of blood pressure and organ perfusion. In septic shock, NO produced by inducible NO-synthase (NOS) has been claimed to mediate pathological vasodilation and cell injury, while NO produced by constitutive NOS may be protective in counteracting hypoperfusion and organ injury. LÄS MER

3. 2. Hyaluronan in sepsis : A clinical and experimental study

   Författare :Sören Berg; Steven J. Allen; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : Sepsis and septic shock are important causes of morbidity and mortality in the intensive care unit (ICU). Mortality rates in septic shock are estimated to be 40-50%, in spite of modem intensive care. Death is commonly caused by cardiovascular collapse and multiple organ dysfunction syndrome (MODS). LÄS MER

4. 3. Glucocorticoid receptors in severe inflammation : Experimental and clinical studies

   Författare :Maria Bergquist; Göran Hedenstierna; Christian Rylander; Catharina Lindholm; Cecile Martijn; Djillali Annane; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glucocorticoid receptor; sepsis; inflammation; flow cytometry; Klinisk immunologi; Clinical Immunology;

   Sammanfattning : Septic shock is one of the most common causes of mortality in intensive care, in spite of antibiotic treatment. Glucocorticoid treatment can be used to blunt an overwhelming immune response in severe inflammation. LÄS MER

5. 4. Adjuvant therapies to fluid resuscitation in experimental sepsis : Intervention studies in models of ARDS and peritonitis

   Författare :Annelie Barrueta Tenhunen; Gaetano Perchiazzi; Johanna Hästbacka; Uppsala universitet; []
   Nyckelord :Acute respiratory distress syndrome; edema formation; peritonitis; sepsis; fluid resuscitation; animal model; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

   Sammanfattning : Fluid resuscitation is essential to antagonize the deleterious effects of tissue hypo-perfusion in sepsis. If not thoroughly monitored and individually tailored, fluid therapy increases the risk of volume overload. Volume overload is associated with higher mortality in sepsis. LÄS MER

7. 5. The Microcirculation in Trauma and Sepsis

   Författare :Peter Bansch; Anestesiologi och intensivvård; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microcirculation; prostacyclin; plasma vilume; trauma; sepsis; sidestream darkfield imaging; albumin; volume expansion; transcapillary escape rate; glycocalyx; charge;

   Sammanfattning : The microcirculation plays a vital part for fluid-, gas- and solute-exchange, and changes in permeability during trauma or sepsis, that are in part necessary for the natural healing process, may also cause hypovolemia and edema formation, leading to disturbances in microvascular exchange. This thesis discusses changes is microvascular flow, permeability and plasma volume (PV) loss after experimental or surgical trauma and experimental sepsis. LÄS MER