Sökning: "Experimental models"
Visar resultat 1 - 5 av 2329 avhandlingar innehållade orden Experimental models.
1. Experimental Evolution : and Fitness Effects of Mutations
Sammanfattning : Bacteria have small, streamlined genomes and evolve rapidly. Their large population sizes allow selection to be the main driver of evolution. With advances in sequencing technologies and precise methods for genetic engineering, many bacteria are excellent models for studying elementary questions in evolutionary biology. LÄS MER
2. Novel treatments of glioblastoma in experimental models
Sammanfattning : One of the major problems with malignant brain tumours, such as glioblastoma multiforme, is that despite being able to remove the major bulk of the tumour through surgery and treating the patients with chemotherapy and radiotherapy, we know that tumour cells have already spread throughout the brain. Furthermore, we now know that the glioblastoma cells effectively suppress the patients’ own anti-tumour response. LÄS MER
3. On cyclic accumulation models for degradation of railway foundations
Sammanfattning : The degradation of railway foundations due to the repeated loading of traffic induces maintenance and safety obligations for the track operator. One major contributor to track degradation is the accelerated settlement rates in soft soils below the track that lead to alignment issues, especially at stiffness transitions. LÄS MER
4. Experimental validation of dynamic component models
Sammanfattning : Proper coil function is an important issue regardingair-handling devices. Thus, proper modeling is important. Thepresent work deals with simulation of heating coil subsystems,especially validation on component level. LÄS MER
5. Experimental Chagas disease
Sammanfattning : The main focus of this thesis was to develop and utilise experimental models using the protozoan parasite Trypanosoma cruzi. We were especially interested in studying the activation of NK cells early after T. cruzi infection and what factors that predispose to a chronic inflammatory disease after T. cruzi infection. LÄS MER