Sökning: "Ex vivo skin"

Visar resultat 1 - 5 av 30 avhandlingar innehållade orden Ex vivo skin.

1. 1. Microvascular inflammatory response in the skin

   Författare :Vladimir Evilevitch; Lunds universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tomografi; medicinsk instrumentering; Physiology; Fysiologi; radiologi; Klinisk fysiologi; medical instrumentation; tomography; radiology; Clinical physics; sodium nitroprusside; terbutaline; anandamide; TRPV1; skin prick test; vanilloid receptor; skin microcirculation; laser Doppler imaging; Plasma exudation; vasodilatation;

   Sammanfattning : This thesis examines the microvascular inflammatory response in the skin. The microvascular response includes vasodilatation and plasma exudation. In the first three studies, the combined response was measured in guinea pig skin with a technique based on detection of radiolabelled protein. LÄS MER

3. 2. Treatment of Skin Wounds with Cell Transplantation and Gene Transfer

   Författare :Tor Svensjö; Lunds universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pigs; gene regulation; cell culture; fibroblasts; keratinocytes; wound healing; skin; gene transfer; Transplantation; gene therapy; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

   Sammanfattning : Background: A large number of different wound coverings have been used in order to improve the wound microenvironment, and thus accelerate repair. Since almost two centuries, clinicians and researchers have developed techniques for skin transplantation. LÄS MER

4. 3. Topical formulations, design and drug delivery : "A dive into water"

   Författare :Abdullah Ali; Marie Lodén; Anan Yagmur; Anders Hall; Malmö universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; water; topical formulations; Pickering emulsion; skin cream; drug delivery; tactile friction; sensory panel; nasal; buccal; mucosa; skin; triglycerides; ethanol; drug transport; cosmetic appeal;

   Sammanfattning : Water is a vital component regulating the properties of topical formulations and their interaction with biological barriers, such as skin and mucosa. Changing the watercontent within the frame of the pharmaceutical triangle will have a huge impact on which type of formulation, such as a cream, ointment, gel, or lotion, is formed, as well as the physical properties of the formulation. LÄS MER

5. 4. Selected aspects on improving the management of skin cancer

   Författare :John Paoli; Göteborgs universitet; []
   Nyckelord :skin cancer; malignant melanoma; squamous cell carcinoma; basal cell carcinoma; multiphoton laser scanning microscopy; penile intraepithelial neoplasia; photodynamic therapy; nerve block; field cancerization; screening; prevention;

   Sammanfattning : The constant rise of skin cancer incidence rates in Sweden is a problem which requires attention. Improved techniques for prevention, early detection and effective treatment are required to face this challenging task. LÄS MER

7. 5. Exploring nanosystems for biomedical applications focusing on photodynamic therapy and drug delivery

   Författare :Vladimir Kirejev; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Photodynamic therapy; PDT enhancement; Nitric oxide; NO-based PDT; Targeted drug delivery; Galectin-3; mTHPP; Cyclodextrin; CD-mTHPP conjugate; PpIX AuNP combination; Two-photon microscopy; FLIM; Cell phototoxicity; Ex vivo skin;

   Sammanfattning : The increasing incidences of cancer and related deaths call for the development of new and improved treatment modalities. Photodynamic therapy (PDT) today is an alternative to conventional treatments, but has limitations. This thesis explores different nanosystems with aim to improve PDT focusing on spectroscopic and ex vivo studies. LÄS MER