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1. 1. In vivo and in vitro models for determination of antiviral activity and resistance

   Författare :Ewa Ljungdahl Ståhle; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The AIDS epidemic has been the driving force for the discovery of substances that inhibit the replication of human immunodeficiency virus (HIV). Much interest has earlier focused on a single gene product central to the life cycle of HIV and to all other retroviruses: the reverse transcriptase (RT), the enzyme responsible for synthesis of DNA from viral RNA. LÄS MER