Sökning: "Estrogen"

Visar resultat 16 - 20 av 417 avhandlingar innehållade ordet Estrogen.

  1. 16. Estrogen signaling in stroke : genetic and experimental studies

    Författare :Magnus Strand; Tommy Olsson; Jan Hillert; Umeå universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; intracerebral hemorrhage; ischemic stroke; genetics; ERα; OPG; 17β-estradiol; enriched environment; learning and memory; hippocampus; NGFI-A; Medicine; Medicin;

    Sammanfattning : Stroke is a common and multifactorial disease influenced by genetic and environmental risk factors. It is a highly heterogeneous entity consisting of two main types, ischemic (80%) and hemorrhagic (20%) stroke. The most common form of hemorrhagic stroke is intracerebral hemorrhage (ICH). LÄS MER

  3. 17. Erythropoietin receptor in growth control and anti-estrogen resistance of estrogen receptor positive breast cancer

    Författare :Susann Reinbothe; Avdelningen för translationell cancerforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tamoxifen resistance; proliferation; PI3k pathway; Breast cancer; erythropoietin receptor; estrogen receptor;

    Sammanfattning : The main function of Erythropoietin (EPO) and its receptor (EPOR) is the stimulation of erythropoiesis. Therefore, recombinant human EPO (rhEPO) is used to treat anemia in cancer patients, but some studies have reported that rhEPO treatment might promote tumor progression. Additionally, EPOR expression has been detected in various cancer forms. LÄS MER

  4. 18. G protein-coupled receptor regulation: The role of protein interactions and receptor trafficking

    Författare :Caroline Sandén; Drug Target Discovery; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; receptor trafficking; B1 receptor; receptor oligomerization; estrogen; GPER1; G protein-coupled estrogen receptor 1; EP24.15; BK; bradykinin; B1R; B2R; B2 receptor; GPCR; receptor maturation;

    Sammanfattning : The superfamily of G protein-coupled receptors (GPCR) is the largest gene family in the human genome. GPCR-mediated signaling operates in every human cell, and about 50% of existing clinically useful drugs act through GPCR. LÄS MER

  5. 19. Estrogen receptors and inflammation in colorectal cancer. Role in prognosis and therapeutic opportunities

    Författare :Geriolda Topi; Malmö Cellpatologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal Cancer; Estrogen Receptor alpha; Estrogen receptor beta; Prognosis and survival; Zebrafish; Metastasis; ERB-041; PPT; AZD9496; Mast cells; Cysteinyl leukotriene receptors;

    Sammanfattning : .... LÄS MER

  7. 20. Pharmacological Modulation of Skeletal Homeostasis

    Författare :Niklas U. Andersson; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Farmakologi; toxicology; farmakognosi; farmaci; toxikologi; pharmacy; pharmacognosy; Pharmacological sciences; peripheral quantitative computed tomography.; dual energy X-ray absorptiomenty; estrogen; parathyroid hormone; gastrectomy; alendronate; ovariectomy; Bone;

    Sammanfattning : Both ovariectomy (OVX) and gastrectomy (GX) cause osteopenia in several animal species including humans. While the effect of OVX has been ascribed to estrogen deficiency, the underlying mechanism behind GX-induced osteopenia is poorly understood. LÄS MER