Sökning: "Estrogen receptor-beta"
Visar resultat 1 - 5 av 34 avhandlingar innehållade orden Estrogen receptor-beta.
1. Genetics of Parkinson's disease - with focus on genes of relevance for inflammation and dopamine neruon development
Sammanfattning : Abstract GENETICS OF PARKINSON’S DISEASE - WITH FOCUS ON GENES OF RELEVANCE FOR INFLAMMATION AND DOPAMINE NEURON DEVELOPMENT Introduction: The risk to be affected by Parkinson’s disease (PD) is considered to be influenced by genetic factors. In some rare cases of familial PD, mutations in some specific genes are known to cause the disease, but in the more common sporadic form of PD the causes are probably environmental factors interacting with genetic vulnerability. LÄS MER
2. Role of estrogen receptor beta in epithelia lacking estrogen receptor alpha expression
Sammanfattning : Estrogens influence the physiology of many organs by activation of the nuclear receptors ERalpha and ERbeta. The epithelium of ventral prostate, ovarian granulosa cells and lung, are ERalpha-negative but express high levels of ERbeta. This thesis focuses on the role played by ERbeta in ERalpha-negative epithelium. LÄS MER
3. Estrogen receptors and inflammation in colorectal cancer. Role in prognosis and therapeutic opportunities
Sammanfattning : .... LÄS MER
4. Breast Cancer Biomarkers with Clinical Relevance Identified by Massively-parallel DNA and RNA Sequencing
Sammanfattning : Women have a 10% lifetime risk of developing breast cancer, and the disease has surpassed lung cancer as the most frequently diagnosed type of cancer in the world. Breast cancer originates in the epithelial cells of the mammary gland and tumor cells have undergone a series of genetic and phenotypic changes that confer tumor promoting properties. LÄS MER
5. Estrogen receptor alpha and beta in breast cancer - gene expression profiles and clinical implications
Sammanfattning : Breast cancer is the most common malignancy in women in the Western world with about 10% of women developing breast cancer during their lifetime, of which one third will eventually succumb to the metastatic form of the disease. Breast cancer arises from the epithelial cells of the breast mammary gland, but the mechanisms involved in tumor initiation, progression, and metastasis are still not fully understood. LÄS MER
