Sökning: "Esophageal morbidity"

Visar resultat 6 - 10 av 16 avhandlingar innehållade orden Esophageal morbidity.

  1. 6. Cardiopulmonary adaption to one-lung ventilation and neoadjuvant therapy during treatment of esophageal cancer

    Författare :Mikael Lund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Introduction: Esophagectomy is the main form of curative treatment for esophageal cancer and has a high morbidity rate. Neoadjuvant chemo- (CT) or chemoradiotherapy (CRT) is employed to increase long-term survival. To improve perioperative care the effects of measures taken to improve surgical exposure i.e. LÄS MER

  3. 7. Studies on alcoholic liver disease

    Författare :Knut Stokkeland; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :alcohol cirrhosis; cytochromes; autoantibodies; mortality; morbidity; prognosis; epidemiology; esophageal varices; lifetime drinking; lifetime alcohol intake;

    Sammanfattning : The overall aim of this thesis was to explore the impact of alcoholic cirrhosis in Sweden, and the relation between drinking patterns and beverage types and alcoholic cirrhosis, and to evaluate the possible role of autoantibodies in the pathogenesis of alcohol related liver disease. We found that rats had appearance of IgG against rat CYP3A 1 and CYP2E 1 during chronic ethanol feeding We found that patients had reactivity against CYP3A4 and CYP2E I in about 20 to 30% and 10 to 20% of the alcoholic sera. LÄS MER

  4. 8. Aspects of neoadjuvant therapy in the curative treatment of cancer in the esophagus or gastroesophageal junction

    Författare :Fredrik Klevebro; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Malignant esophageal tumors are among the most severe cancers. Only about 30% of the patients are suitable for curative treatment at diagnosis. The treatment is extremely demanding and unfortunately has disappointing results. The staging of disease and the treatment for cancer of the esophagus and gastroesophageal junction need to be improved. LÄS MER

  5. 9. Perioperative complications in obese patients : A thesis on risk reducing strategies

    Författare :Fredrik Ander; Lars Berggren; Rebecca Ahlstrand; Alex de Leon; Johan Raeder; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Intubation time; videolaryngoscopy; obesity; esophagogastric junction; remifentanil; esmolol; high-resolution manometry; pulmonary aspiration; postoperative pain; postoperative opioid-sparing;

    Sammanfattning : Aspiration of gastric content and delayed or failed intubation are the leading causes of anesthesia-related mortality and morbidity. In the recovery period, airway obstruction with subsequent hypoxia is a relatively common cause of morbidity, and is highly associated to the amount of opioids administered, especially in obese patients. LÄS MER

  7. 10. Aspects on prognosis of cancers of the oesophagus and gastric cardia

    Författare :Martin Sundelöf; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Oesophagus; adenocarcinoma; squamous-cell carcinoma; gastric cardia; prognosis; lifestyle factors; palliation; dysphagia;

    Sammanfattning : Oesophageal cancer is an aggressive form of cancer with a poor prognosis. The two main histological types are squamous-cell carcinoma and adenocarcinoma. In the Western world the incidence rate of adenocarcinoma of the oesophagus, previously rather rare, has shown a dramatic increase in recent decades. LÄS MER