Sökning: "Escherichia coli"

Visar resultat 11 - 15 av 568 avhandlingar innehållade orden Escherichia coli.

  1. 11. Evolution and Mechanisms of Tigecycline Resistance in Escherichia coli

    Författare :Marius Linkevičius; Dan I. Andersson; Linus Sandegren; Patrice Courvalin; Uppsala universitet; []
    Nyckelord :Tigecycline; Bacterial resistance; Fitness; Escherichia coli; AcrAB; LPS; Tet proteins; Tet A ; Tet K ; Tet M ; Tet X ; tet genes; pUUH239.2; Mikrobiologi; Microbiology;

    Sammanfattning : Antibiotic resistance is an ongoing global medical crisis and we are in great need of new antibacterial agents to combat rapidly emerging resistant pathogens. Tigecycline is one of few drugs that have been introduced into medicine during the last two decades. LÄS MER

  3. 12. Mechanisms and Dynamics of Mecillinam Resistance in Escherichia coli

    Författare :Elisabeth Thulin; Dan I Andersson; Laura Piddock; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mecillinam; Antibiotic resistance; Escherichia coli; Urinary tract infections; Fitness; Penicillin binding proteins; cysteine biosynthesis; Mikrobiologi; Microbiology;

    Sammanfattning : The introduction of antibiotics in healthcare is one of the most important medical achievements with regard to reducing human morbidity and mortality. However, bacterial pathogens have acquired antibiotic resistance at an increasing rate, and due to a high prevalence of resistance to some antibiotics they can no longer be used therapeutically. LÄS MER

  4. 13. Structural and Genetic Studies of Translation in Escherichia coli

    Författare :Qing Zhao; Leif Isaksson; Lars-Göran Öfverstedt; Odd Nygård; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; electron tomography; ribosome; 30S subunit; 50S subunit; rifampicin; Escherichia coli; Translation initiation; Initiation codon; Downstream Region DR ; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar;

    Sammanfattning : Ribosomes are the universal ribonucleoprotein organelles that translate the genetic message from mRNA to protein. In prokaryotes, the ribosomal subunits are 30S and 50S subunit, which bind together during the translation process forming 70S ribosome. LÄS MER

  5. 14. From protein production to genome evolution in Escherichia coli

    Författare :Susan Schlegel; Jan-Willem de Gier; Peter Neubauer; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Escherichia coli; BL21 DE3 ; protein production; membrane proteins; secretory proteins; genome evolution; Biochemistry; biokemi;

    Sammanfattning : The aim of my Ph.D. studies was to improve production yields of membrane- and secretory proteins in the widely used E. coli protein production strain BL21(DE3). LÄS MER

  7. 15. Studies on Translation Initiation and Termination in Escherichia coli

    Författare :Georgina Ibrahim Isak; Leif Isaksson; Suparna Sanyal; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Escherichia coli; translation; ribosome; IF1; RF1; kasugamycin; tRNA; molekylärgenetik; Molecular Genetics;

    Sammanfattning : Translation initiation factor 1 (IF1) has been shown to be an RNA chaperone. In order to find functional interactions that IF1 may have with rRNA, we have isolated second-site suppressors of a cold-sensitive IF1 mutant. LÄS MER