Sökning: "Erika Roman"

Visar resultat 6 - 10 av 15 avhandlingar innehållade orden Erika Roman.

  1. 6. Distribution and Long-term Effects of the Environmental Neurotoxin β-N-methylamino-L-alanine (BMAA) : Brain changes and behavioral impairments following developmental exposure

    Författare :Oskar Karlsson; Eva Brittebo; Nils Gunnar Lindquist; Erika Roman; Sandra Ceccatelli; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ALS PDC; Guam; Developmental neurotoxicity; Brain growth spurt; Behavior; Nonprotein amino acid; Excitotoxic; Cyanobacteria; Apoptosis; BMAA; environmental toxin; Algal blooming; Algblomning; algtoxin; alggift; hjärnutveckling; Toxicology; Toxikologi; Toxicology; Toxikologi;

    Sammanfattning : Many cyanobacteria are reported to produce the nonprotein amino acid β-N-methylamino-L-alanine (BMAA). Cyanobacteria are extensively distributed in terrestrial and aquatic environments and recently BMAA was detected in temperate aquatic ecosystems, e.g. the Baltic Sea. LÄS MER

  3. 7. The Biological Importance of the Amino Acid Transporter SLC38A10 : Characterization of a Knockout Mouse

    Författare :Frida A. Lindberg; Robert Fredriksson; Erika Roman; Karin Nordenankar; Vootele Vöikar; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Solute carrier; SLC; SNAT10; SLC38A10; phenotyping; behavior; amino acids; knockout mouse model; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : The biggest group of transporters, the solute carriers (SLCs), has more than 400 members, and about 30% of these are still orphan. In order to decipher their biological function and possible role in disease, there is a need for characterization of these. LÄS MER

  4. 8. Adolescent behavior : Links to early-life stress and alcohol in male and female rats

    Författare :Stina Lundberg; Erika Roman; Ingrid Nylander; Heidi MB Lesscher; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adolescence; alcohol exposure; behavior; corticosterone; dynorphin; early life; endogenous opioid peptides; Met-enkephalin-Arg6Phe7 MEAP ; individual differences; multivariate concentric square field MCSF ; phenotyping; radioimmunoassay; selective breeding for alcohol consumption; voluntary alcohol intake; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : Adolescence is an important developmental phase with large changes in behavior, physiology and neurobiology, which transform an individual from immature child to independent adult. Due to these changes, adolescence is a sensitive period for exposure to environmental factors such as stress and drug exposure; it is also a common age of onset for alcohol consumption as well as several psychiatric disorders. LÄS MER

  5. 9. Examining Female Resilience to Early Environmental Influences : Short- and long-term consequences on behaviour, HPA axis activity and alcohol intake after prolonged maternal separation

    Författare :Stina Lundberg; Erika Roman; Ingrid Nylander; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adolescence; Adulthood; Corticosterone; Early-life stress; Handling; Maternal deprivation; Multivariate concentric square field; MCSF; Sex differences; Social play behavior; Stress reactivity; Supplier differences; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : Early-life experiences are an important factor influencing further development of the individual. Adverse experiences early in life, such as various kinds of abuse or neglect, are types of early-life stress that can adversely affect an individuals health, as well as contribute to the development of an array of disorders later in life. LÄS MER

  7. 10. Individual differences in behavior, neurochemistry and pharmacology associated with voluntary alcohol intake

    Författare :Shima Momeni; Erika Roman; Bo Söderpalm; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intermittent access; multivariate concentric square field; open field; risk assessment; risk taking; individual difference; behavior; strain variation; endogenous opioid system; naltrexone; Pharmaceutical Science; Farmaceutisk vetenskap;

    Sammanfattning : Alcohol use disorder is a worldwide public health problem and is a disorder with substantial individual variation. There are suggested links between various behavioral traits, comorbid psychiatric diseases and excessive alcohol consumption. LÄS MER