Sökning: "Erik Aurell"

Visar resultat 1 - 5 av 8 avhandlingar innehållade orden Erik Aurell.

1. 1. Statistical models of TF/DNA interaction

   Författare :Aymeric Fouquier d'Herouel; Erik Aurell; Otto Berg; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; gene expression; regulation; transcription factor; binding motif; matrix representations; gibbs sampling; binding affinity; non-specific binding; Biological physics; Biologisk fysik;

   Sammanfattning : Gene expression is regulated in response to metabolic necessities and environmental changes throughout the life of a cell. A major part of this regulation is governed at the level of transcription, deciding whether messengers to specific genes are produced or not. LÄS MER

3. 2. On state space structure and average case complexity in random K-SAT problems

   Författare :John Ardelius; Erik Aurell; Bart Selman; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Computer science; Datavetenskap;

   Sammanfattning : This thesis gives an introduction to a currently active area in the cross-section between theoretical computer science and theoretical physics. In the last ten years it has been suggested that critical behaviour, usually seen in models from condensed matter physics, may be responsible for the intractability of NP complete computation problems. LÄS MER

4. 3. Equilibrium and Dynamics on Complex Networkds

   Författare :Gino Del Ferraro; Erik Aurell; Bernard Derrida; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Statistical mechanics; complex networks; spin systems; non equilibrium dynamics; generalized belief propagation; message passing; cavity method; variational approaches; Fysik; Physics;

   Sammanfattning : Complex networks are an important class of models used to describe the behaviour of a very broad category of systems which appear in different fields of science ranging from physics, biology and statistics to computer science and other disciplines. This set of models includes spin systems on a graph, neural networks, decision networks, spreading disease, financial trade, social networks and all systems which can be represented as interacting agents on some sort of graph architecture. LÄS MER

5. 4. On diverse biophysical aspects of genetics : from the action of regulators to the characterization of transcripts

   Författare :Aymeric Fouquier D´Hérouel; Erik Aurell; Felix Ritort; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; transcription regulation; regulatory motifs; binding affinity; genetic interactions; secondary structure; sequence repeats; transcript characterization; Biological physics; Biologisk fysik;

   Sammanfattning : Genetics is among the most rewarding fields of biology for the theoretically inclined, offering both room and need for modeling approaches in the light of an abundance of experimental data of different kinds. Many aspects of the field are today understood in terms of physical and chemical models, joined by information theoretical descriptions. LÄS MER

7. 5. Data Analysis and Next Generation Sequencing : Applications in Microbiology

   Författare :Nicolas Innocenti; Erik Aurell; Mogens Jensen; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; RNA-seq; tagRNA-seq; primary and processed RNA; Enterococcus faecalis; Complex transcription; Metagenomics; 5 tagRACE; minimal absent words; compressed sensing; metagenomics; bacterial community reconstruction; Biologisk fysik; Biological Physics;

   Sammanfattning : Next Generation Sequencing (NGS) is a new technology that has revolutionized the way we study living organisms. Where previously only a few genes could be studied at a time through targeted direct probing, NGS offers the possibility to perform measurements for a whole genome at once. LÄS MER