Sökning: "Epithelial barrier function"

Visar resultat 21 - 25 av 72 avhandlingar innehållade orden Epithelial barrier function.

  1. 21. Studies on CAR and CLMP : two proteins of epithelial tight junctions

    Författare :Elisabeth Raschperger; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Tight junctions are important structures for the function of epithelial cells. They are composed of multi-protein complexes that connect the plasma membranes of two adjacent epithelial cells to each other and function as paracellular barriers, which regulate flux of ions, solutes, proteins and cells across the epithelium. LÄS MER

  3. 22. Mast Cell-Mediated Orchestration of Airway Epithelial Responses in Chronic Respiratory Diseases

    Författare :Frida Berlin; Respiratorisk cellbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mast cell; Tryptase; Chymase; Bronchial epithelium; Respiratory diseases;

    Sammanfattning : Chronic respiratory diseases, such as asthma, are an increasing health issue worldwide and cause about 3.9 million deaths annually. Despite this, little is know about the molecular mechanisms underpinning disease pathogenesis. LÄS MER

  4. 23. Classical cadherins and the thyroid. Studies on organ development and epithelial differentiation

    Författare :Mats Grände; Göteborgs universitet; []
    Nyckelord :Thyroid; cadherin; TGF-; EGF; MEK; development; EMT;

    Sammanfattning : The cadherins are key regulators of tissue patterning and organ formation. E-cadherin is important for cell-cell adhesion and promotes epithelial morphogenesis and maintenance of the epithelial phenotype. LÄS MER

  5. 24. On the role of HMGB1 and IL-1 in tissue barrier defense

    Författare :Cecilia Zetterström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The specialized epithelial surfaces of the lymphoepithelial tissue in the airways and the seminiferous epithelium of the testis are sites of host-environmental interaction at the same time as they serve important physiological functions in gas exchange and reproduction. The host response of a broken epithelial barrier requires rapid mechanisms to control the microflora and to prevent invasion of pathogens. LÄS MER

  7. 25. Staphylococcus aureus alpha-toxin : natural fragments and effects on intestinal epithelial cells

    Författare :Young-Keun Kwak; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Staphylococcus aureus is a human pathogen, commonly found in healthy humans as a part of normal flora. alpha-toxin is thought to be largely responsible for the pathogenesis of the bacterium. LÄS MER