Sökning: "Enzyme mimic"

Visar resultat 1 - 5 av 38 avhandlingar innehållade orden Enzyme mimic.

  1. 1. Gene therapy tools: oligonucleotides and peptides

    Författare :Jonas Eriksson; Ülo Langel; Jens Kurreck; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Gene therapy; oligonucleotide; peptide; RNA-cleaving deoxyribozyme; deoxyribozyme; DNAzyme; cell-penetrating peptide; CPP; enzyme; enzyme kinetics; kinetic assay; assay; telomerase; telomerase inhibitor; imetelstat; GRN163L; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : Genetic mutations can cause a wide range of diseases, e.g. cancer. Gene therapy has the potential to alleviate or even cure these diseases. LÄS MER

  3. 2. Experimental and computational exploration of enzyme sequence space

    Författare :Elzbieta Rembeza; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; high-throughput-screening; protein annotation; enzyme discovery; enzyme sequence space; oxidases;

    Sammanfattning : Millions of enzymes with desirable features or new exciting activities can be found in organisms occupying diverse niches all around the earth. However, enzyme studies tend to be biased towards characterisation of representatives from eukaryotes, model organisms, or disease-causing bacteria. LÄS MER

  4. 3. Multifunctional silk: from fabrication to application

    Författare :Manish Singh; Tillämpad biokemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Silk; Sonochemistry; Supercritical impregnation; Nanofiller; Soft biosensor; Enzyme mimic;

    Sammanfattning : Silk fibers offer untapped internal structures to template the formation of nano-objects and active coatings. So far, access to all or part of the internal and organized structures has been a significant challenge. LÄS MER

  5. 4. Design and Synthesis of Enzyme Inhibitors Against Infectious Diseases : Targeting Hepatitis C Virus NS3 Protease and Mycobacterium tuberculosis Ribonucleotide Reductase

    Författare :Johan Gising; Mats Larhed; Anders Karlén; Victor Snieckus; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicinal Chemistry; Läkemedelskemi;

    Sammanfattning : Infectious diseases, including hepatitis C and tuberculosis, claim the lives of over 15 million people each year. Hepatitis C is caused by the hepatitis C virus (HCV) which infects the liver and can ultimately result in liver transplantation. HCV is very adaptive as a result of its high mutation rate. LÄS MER

  7. 5. Computational Studies and Design of Biomolecular Diels-Alder Catalysis

    Författare :Mats Linder; Tore Brinck; Kendall N. Houk; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Computational chemistry; density functional theory; enzyme design; molecular modeling; organocatalysis; stepwise Diels-Alder; oxyanion hole;

    Sammanfattning : The Diels-Alder reaction is one of the most powerful synthetic tools in organic chemistry, and asymmetric Diels-Alder catalysis allows for rapid construction of chiral carbon scaffolds. For this reason, considerable effort has been invested in developing efficient and stereoselective organo- and biocatalysts. LÄS MER