Sökning: "Enheten för psykiatrisk neuromodulering PNU"

Hittade 5 avhandlingar innehållade orden Enheten för psykiatrisk neuromodulering PNU.

  1. 1. A Glial Role in the Action of Electroconvulsive Therapy

    Författare :Malin Wennström; Enheten för psykiatrisk neuromodulering (PNU); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psykiatri; klinisk psykologi; psykosomatik; psychosomatics; clinical psychology; Psychiatry; Hippocampus; Depression; Gliogenesis; Electroconvulsive seizures;

    Sammanfattning : The aim of the current thesis was to investigate glial responses to electroconvulsive seizures (ECS), an animal model of the fast-acting antidepressant treatment electroconvulsive therapy (ECT). Depression, a common and devastating disorder, has in recent years been associated with volumetric changes in prefrontal cortex, hippocampus and amygdala, brain regions known to be implicated in emotional behavior. LÄS MER

  3. 2. Modulation of angiogenesis in adult rat brain - effect of aging, stress, environmental enrichment and antidepressant treatment

    Författare :Joakim Ekstrand; Enheten för psykiatrisk neuromodulering (PNU); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; corticosterone; enrichment; electroconvulsive seizures; Angiogenesis; neurogenesis;

    Sammanfattning : Neurogenesis and angiogenesis are stimulated by a number of antidepressant treatments, and cellular plasticity has emerged as a phenomenon with great relevance to the etiology and treatment of depression. In paper I we characterize how ECS-induced endothelial cell proliferation leads to vascularization of the adult rat hippocampus. LÄS MER

  4. 3. Neurogenic and angiogenic actions of electroconvulsive seizures in adult rat brain

    Författare :Johan Hellsten; Enheten för psykiatrisk neuromodulering (PNU); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vävnadskultur; Psychiatry; clinical psychology; psychosomatics; klinisk psykologi; psykosomatik; histokemi; cytokemi; Histologi; tissue culture; histochemistry; cytochemistry; Histology; Biology; Biologi; electroconvulsive seizures; hippocampus; depression; angiogenesis; neurogenesis; Psykiatri;

    Sammanfattning : In the current thesis, the neurogenic and angiogenic response to electroconvulsive seizure (ECS)-treatment was investigated in the adult rat brain. ECS-treatment is an animal model for the antidepressant treatment electroconvulsive therapy (ECT), which is considered to be the most effective antidepressant treatment modality today, however with not yet fully understood modes of action. LÄS MER

  5. 4. Characterization of habenular neurocircuitry. A potential novel target for treating depression

    Författare :Jonas Jester-Broms; Enheten för psykiatrisk neuromodulering (PNU); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : In the last decade, there has been an explosion of interest within the psychiatric research community in a small diencephalic brain region called the habenula. It has been uncovered as a key regulator of monoaminergic transmission, playing a fundamental role in decision making, behavioral flexibility, inhibitory control, sleep, pain and analgesia. LÄS MER

  7. 5. Lithium and brain plasticity - studies on glial cell changes and electroconvulsive treatment-induced amnesia in rats

    Författare :Karin Orre; Enheten för psykiatrisk neuromodulering (PNU); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lithium; electroconvulsive seizures; mood disorder; gliogenesis; amnesia; oligodendrogenesis; myelination; NG2 cells;

    Sammanfattning : Depression and bipolar disorder, collectively known as mood disorders, are devastating, common and often chronic illnesses. Imaging studies of patients with mood disorders have demonstrated structural changes in several brain regions implicated in mood regulation. LÄS MER