Sökning: "Endothelial function"

Visar resultat 11 - 15 av 380 avhandlingar innehållade orden Endothelial function.

  1. 11. Reproductive and Metabolic Consequences of the Polycystic Ovarian Syndrome

    Författare :Miriam Hudecova; Inger Sundström Poromaa; Jan Holte; Matts Olovsson; Per Olof Janson; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; polycystic ovarian syndrome; long-term follow-up; ovarian reserve; anti-Müllerian hormone; insulin sensitivity; early insuline response; impaired glucose tolerance; diabetes; endothelial function; endothelial-dependent vasodilation; Obstetrics and gynaecology; Obstetrik och gynekologi; Obstetrik och gynekologi; Obstetrics and Gynaecology;

    Sammanfattning : Polycystic ovary syndrome (PCOS) is a complex clinical condition characterized by hyperandrogenism and chronic oligo/anovulation. Infrequent ovulation and metabolic alterations in women with PCOS are associated with subfertility and probably increased miscarriage rates compared with normal fertile women. LÄS MER

  2. 12. Effects of physical exercise on coronary and peripheral vascular function. An integrative physiological study from rat to man

    Författare :Ulrika Hägg Samuelsson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :exercise; endothelial function; coronary flow velocity reserve; colour Doppler echocardiography; oxidative stress; gene expression; stiffness; ultrasound biomicroscopy;

    Sammanfattning : Physical exercise is beneficial for the cardiovascular health. Numerous epidemiological studies reveal that physical activity reduces the risk of cardiovascular related death. Nevertheless, the underlying vessel wall specific physiological and molecular mechanisms still remain incompletely understood. LÄS MER

  3. 13. Molecular Mechanisms in Endothelial Cell Differentiation

    Författare :Emma Rennel; Pär Gerwins; Lena Claesson-Welsh; Ian Zachary; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; angiogenesis; FGF-2; VEGF-A; signal transduction; in vitro angiogenesis assay; immortalized brain endothelial cells; H-Ras; tetracycline-regulated gene expression; microarray; telomerase immortalized human microvascular endothelial cells; differentiation; Patologi; Pathology; Patologi;

    Sammanfattning : Angiogenesis is the formation of new blood vessels from the pre-existing blood vessels. Blood vessels are composed of endothelial cells and supporting musculature. Angiogenesis is regulated by numerous soluble ligands and by cell-matrix interactions. LÄS MER

  4. 14. Vascular endothelial growth factor receptors in angiogenesis

    Författare :Kui Huang; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; endothelial cells; VEGF receptor; signal transduction; pertide; angiogenesis; Genetik; Clinical genetics; Klinisk genetik; Medical Biochemistry; medicinsk biokemi;

    Sammanfattning : Angiogenesis is a process in which new capillaries sprout from preexisting blood vessels. Vascular endothelial growth factor (VEGF) promotes endothelial cell proliferation and migration and thereby stimulates angiogenesis. VEGF receptors (VEGFRs) have been implicated as key regulatory components in endothelial cells. LÄS MER

  5. 15. Mechanisms for leukocyte-mediated adjustment of endothelial barrier function

    Författare :Narinder Gautam; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Inflammation; leukocyte extravasation; endothelial cells; vascular permeability; plasma leakage integrin signaling; heparin binding protein; contact phase; bradykinin.;

    Sammanfattning : Extravasation of polymorphonuclear leukocytes (PMN) and associated plasma exsudation are key events in the inflammatory process. The mechanism by which activated PMN may induce increased vascular permeability for macromolecules is not fully understood but crucially dependent on an intact leukocytic beta2 integrin (CD11/CD18) adhesion receptor function. LÄS MER