Sökning: "Endothelial cells"

Visar resultat 11 - 15 av 685 avhandlingar innehållade orden Endothelial cells.

  1. 11. Hyaluronan receptors of liver endothelial cells, their purification and characterisation

    Författare :Peter A. G. McCourt; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; hyaluronan; scavenger receptors; ICAM-1; liver endothelial cells; Biokemi; Biochemistry; Biokemi; fysiologi; Physiology;

    Sammanfattning : Hyaluronan (HA) is a polysaccharide common throughout the connective tissues. and is found at low concentrations in the blood. The major site of its clearance is via an endocytic receptor on liver endothelial cells (LEC). This process is vital, as excessive serum levels of HA lead to clotting disorders and overly viscous blood. LÄS MER

  3. 12. TGFβ Signal Transduction in Endothelial Cells

    Författare :Gudrun Valdimarsdóttir; Peter ten Dijke; Carl-Henrik Heldin; Christer Betsholtz; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Cellbiologi; Cell biology; Cellbiologi;

    Sammanfattning : Transforming growth factor β (TGFβ) is a multifunctional cytokine that is involved in many biological effects, such as proliferation, migration, differentiation and cell survival. TGFβ regulates cellular responses by binding to a heteromeric complex of type I and type II serine/threonine kinase receptors. LÄS MER

  4. 13. The clinical importance of anti-endothelial cell antibodies in chronic kidney dysfunction and organ transplantation

    Författare :Nidia Maritza Hernandez; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endothelial Cells; Anti-endothelial cell antibodies; Organ Rejection; Tissue Engineering;

    Sammanfattning : The endothelium is the thin layer of cells that lines the interior surface of blood vessels and is the first site of contact between immune cells and tissues. Therefore, alterations at the level of the endothelium are crucial to understand the nature of vascular diseases and organ damage. LÄS MER

  5. 14. Towards Generation of Human Hematopoietic Stem Cells from Pluripotent Stem Cells

    Författare :Roger Rönn; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hematopoietic stem cells; pluripotent stem cells; embryonic development.; in vitro differentiation;

    Sammanfattning : There is a pressing need for compatible Hematopoietic Stem Cells (HSCs), in high quantities and of good clinical quality, to ensure optimal treatment for patients with various blood malignancies. Pluripotent Stem Cells (PSCs) have the potential to be a source for generating HSCs. LÄS MER

  7. 15. Effects of some Endocrine Disruptors on Human and Grey Seal Uterine Cells

    Författare :Carolina Bredhult; Matts Olovsson; Britt-Marie Bäcklin; Olle Söder; Uppsala universitet; []
    Nyckelord :Obstetrics and gynaecology; Reproductive toxicology; Baltic grey seal; leiomyoma; myometrial cells; endometrial endothelial cells; hormones; endocrine disruptors; Obstetrik och kvinnosjukdomar;

    Sammanfattning : The effects of environmental contaminants in humans and animals are of great concern. Some contaminants are endocrine disruptors that may interfere with the endogenous hormonal signalling and disturb, for example, reproductive organs and functions. LÄS MER