Sökning: "Endogenous Retrovirus ERV"

Hittade 5 avhandlingar innehållade orden Endogenous Retrovirus ERV.

  1. 1. Novel Bioinformatics Applications for Protein Allergology, Genome-Wide Association and Retrovirology Studies

    Författare :Álvaro Martínez Barrio; Erik Bongcam-Rudloff; Teresa K Attwood; Uppsala universitet; []
    Nyckelord :data integration; web services; protein allergology; risk assessment; cross reactivity; endogenous retroviruses; ERV; dog; canine; GWAS; genome-wide association studies;

    Sammanfattning : Recently, the pace of growth in the amount of data sources within Life Sciences has increased exponentially until pose a difficult problem to efficiently manage their integration. The data avalanche we are experiencing may be significant for a turning point in science, with a change of orientation from proprietary to publicly available data and a concomitant acceptance of studies based on the latter. LÄS MER

  3. 2. Genomic Variation and Evolution of HERV-H and other Endogenous Retroviruses (ERVs)

    Författare :Patric Jern; Jonas Blomberg; Michael Tristem; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; Endogenous Retrovirus ERV ; HERV-H; Phylogeny; Evolution; Sequence Variation; Polymorphism; Recent Integrations; Horizontal Transfer; Master Elements; Taxonomy; Mikrobiologi; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar;

    Sammanfattning : An exogenous retrovirus (XRV) that integrates into a germ cell may be inherited as a Mendelian gene; it becomes an endogenous retrovirus (ERV). The human genome consists of up to 8% HERVs. The gammaretroviral (ERV class I) HERV-H, with 926 members, is the largest ERV group. LÄS MER

  4. 3. Retroviral long Terminal Repeats; Structure, Detection and Phylogeny

    Författare :Farid Benachenhou; Jonas Blomberg; Göran Sperber; Aris Katzourakis; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Retrovirus; long terminal repeats; hidden Markov models; phylogeny; alignment; conserved motif; stem-loop; Clinical virology; Klinisk virologi; Klinisk virologi; Clinical Virology;

    Sammanfattning : Long terminal repeats (LTRs) are non-coding repeats flanking the protein-coding genes of LTR retrotransposons. The variability of LTRs poses a challenge in studying them. Hidden Markov models (HMMs), probabilistic models widely used in pattern recognition, are useful in dealing with this variability. LÄS MER

  5. 4. Retroviral and related nucleic acid processing enzymes expression and detection : Applications on clinical studies of HIV and HERVs

    Författare :Raymond Awad; Amnon Hizi; Uppsala universitet; []
    Nyckelord :Medical sciences; Reverse transcriptase; endogenous retrovirus; deoxycytidine kinase; HIV; HERVS; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medical Virology; medicinsk virologi;

    Sammanfattning : Reverse transcriptase (RT), the expression and detection of the enzyme marking the family Retroviridae, has been studied. A new RT activity assay adapted to 96-well microtitre plates is described. It uses a non- radioactive bromodeoxyuridine triphosphate (BrdUTP) substrate in a solid phase format. The assay was highly sensitive. LÄS MER

  7. 5. Human Endogenous Retroviruses: Expression and Evolutionary Relationships

    Författare :Marie-Louise Andersson; Avdelningen för medicinsk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mikrobiologi; mycology; virology; bacteriology; Microbiology; bakteriologi; expression; transcription; reverse transcriptase; HERV; phylogeny; virologi; mykologi;

    Sammanfattning : The human genome contains genetic elements which are more or less similar to infectious retroviruses. These are called human endogenous retroviruses (HERVs) and are thought to be remnants of infections in the primate lineage. LÄS MER