Sökning: "Endocrine breast cancer"

Visar resultat 1 - 5 av 70 avhandlingar innehållade orden Endocrine breast cancer.

1. 1. Biological profiles of endocrine breast cancer

   Författare :Anna Göthlin Eremo; Sten Wingren; Pia Wegman; Elisabet Tina; Karin Franzén; Agneta Jansson; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocrine breast cancer; tamoxifen; Foxl2; Wwox; ErbB4; HER4; gene expression; randomized patients; Biomedicin; Biomedicine;

   Sammanfattning : .... LÄS MER

3. 2. Predicting Prognosis and Tamoxifen Response in Breast Cancer. With a special focus on contralateral breast cancer

   Författare :Sara Alkner; Bröstcancer-genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; prognosis; treatment prediction; endocrine treatment; tamoxifen; coactivator; AIB1; PAX2; SRC; contralateral breast cancer; premenopausal; randomized trial; mode of detection; mammography.;

   Sammanfattning : One of the great challenges in breast cancer treatment today is to customize adjuvant treatment to each patient’s individual needs. To do this it is necessary to learn more about the prognostic and treatment predictive factors that determine the risk of relapse and response to a certain mode of treatment. LÄS MER

4. 3. Predictive markers for tamoxifen response in primary breast cancer

   Författare :Maria Stendahl; Malmö Patologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; General pathology; Cytologi; onkologi; prognosis; Cytology; oncology; cancerology; predictive marker; p27; cyclin D1; tamoxifen; PR; breast cancer; ER; pathological anatomy; Patologi allmän ; patologisk anatomi;

   Sammanfattning : It is well-known that a majority of breast cancers are hormone-dependent, making endocrine therapy an important adjuvant treatment after surgery. Susceptibility to endocrine treatment is determined by the presence of estrogen receptors (ER) and progesterone receptors (PR) in the tumors. LÄS MER

5. 4. Estrogen receptor alpha and beta in breast cancer - gene expression profiles and clinical implications

   Författare :Sofia Gruvberger; Bröstcancer-genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk biologi; oncology; cancerology; Cytologi; onkologi; cancer; Cytology; artificial neural networks; gene expression profiling; microarray; tamoxifen; adjuvant endocrine therapy; ER; estrogen receptor beta; Breast cancer; estrogen receptor alpha; Clinical biology;

   Sammanfattning : Breast cancer is the most common malignancy in women in the Western world with about 10% of women developing breast cancer during their lifetime, of which one third will eventually succumb to the metastatic form of the disease. Breast cancer arises from the epithelial cells of the breast mammary gland, but the mechanisms involved in tumor initiation, progression, and metastasis are still not fully understood. LÄS MER

7. 5. To predict results of breast cancer therapy

   Författare :Anna Nordenskjöld; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; breast cancer; endocrine therapy; survival;

   Sammanfattning : We have used the almost complete national Swedish Cancer register, regional quality management register and one randomized adjuvant endocrine trial to study, the effect of radiotherapy in breast cancer with 1-3 positive nodes (study 1), the effect of tamoxifen in estrogen receptor (ER)-positive tumors depending on expression of the progesterone receptor (PR) (studies 2 and 4) and the development of the survival rates of breast cancer in Sweden 1989-2013 (study 3) Study 1. We compared relative breast cancer survival in two Swedish health care regions that between 1989 and 2006 had different guidelines for postoperative radiotherapy. LÄS MER