Sökning: "Enantioresolution"
Hittade 4 avhandlingar innehållade ordet Enantioresolution.
1. Chiral Separation of Amines by Non-Aqueous Capillary Electrophoresis using Low Molecular Weight Selectors
Sammanfattning : Three chiral selectors (diketogulonic acid, benzoxycarbonylglycylproline and ketopinic acid) have been introduced for enantioseparation of pharmacologically active amines in non-aqueous capillary electrophoresis. The use of organic solvents, instead of aqueous buffers in the background electrolyte facilitated ion-pair formation between the analytes and the chiral selectors. LÄS MER
2. Enantiomeric Separations using Chiral Counter-Ions
Sammanfattning : This thesis describes the use of chiral counter-ions for the enantiomeric separation of amines in non-aqueous capillary electrophoresis. The investigations have been concentrated on studies of the influence, of the chiral counter-ion, the solvent, the electrolyte and the analyte, on the enantioselective separation. LÄS MER
3. Enantiomeric separation by capillary electrophoresis : With special emphasis on the partial filling technique
Sammanfattning : Capillary electrophoresis as a powerful separation technique was employed for resolution of racemic drugs. Taurodeoxycholate (TDC), different cyclodextrins and α1- acid glycoprotein (AGP) were dissolved in the background electrolyte at low pH (3.0 to 4.0 ) as chiral selectors. LÄS MER
4. Chiral packed capillary chromatography using an in-column immobilized selector : With special emphasis on vancomycin
Sammanfattning : Packed fused silica capillary columns have been used for enantioseparation of drugs and related compounds. The technique to prepare the chiral stationary phase (CSP) involved a reductive amination of aldehyde functionalized silica with a chiral selector. The immobilization was performed in the packed column, thereby minimizing the use of selector. LÄS MER
