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Visar resultat 1 - 5 av 8 avhandlingar som matchar ovanstående sökkriterier.
1. Bioimaging for analysis of protein expression in cells and tissues using affinity reagents
Sammanfattning : The detection and analysis of biomolecules, such as proteins, are of great interest since these molecules are fundamental for life and our health. Due to the complexity of biological processes, there is a great advantage of studying proteins in their natural context, for example by using bioimaging. LÄS MER
2. Integration of RNA and protein expression profiles to study human cells
Sammanfattning : Cellular life is highly complex. In order to expand our understanding of the workings of human cells, in particular in the context of health and disease, detailed knowledge about the underlying molecular systems is needed. LÄS MER
3. Spatiotemporal characterization of the human proteome
Sammanfattning : Characterizing the molecular components of the basic unit of life; the cell, is crucial for a complete understanding of human biology. The cell is divided into compartments to create a suitable environment for the resident proteins to fulfill their functions. LÄS MER
4. Antibody-based subcellular localization of the human proteome
Sammanfattning : This thesis describes the use of antibodies and immunofluorescence for subcellular localization of proteins. The key objective is the creation of an open-source atlas with information on the subcellular location of every human protein. LÄS MER
5. Towards subcellular localization of the human proteome using bioimaging
Sammanfattning : Since the publication of the complete sequence of the human genome in 2003 there has been great interest in exploring the functions of the proteins encoded by the genes. To reveal the function of each and every protein, investigation of protein localization at the subcellular level has become a central focus in this research area, since the localization and function of a protein is closely related. LÄS MER