Sökning: "Elongation factor"

Visar resultat 6 - 10 av 94 avhandlingar innehållade orden Elongation factor.

  1. 6. Torque and Angle Controlled Tightening of Bolted Joints

    Författare :Göran Toth; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; torque controlled tightening; deformation parameters; momentary elongation; deformation factor; torque; Bolted screwed joints; spring characteristic; Torx; torque and angle controlled tightening; hexalobular; final torque; snug torque; Taylor’s series expansions; preload; plastic deformation; permanent elongation; yield; friction diameter; plastic spring constant; clevis; turn-of-nut method; bearing surface pressure; twisting; Monte-Carlo simulations;

    Sammanfattning : Reduced weight and fuel consumption, improved reliability and engine performance are the main requirements in the automotive industry of today. These requirements demand robust and optimized bolted joints, where a high amount of preload obtained by effective utilisation of the bolt is essential. LÄS MER

  2. 7. Insights Into Protein Synthesis - Structural Aspects of Elongation Factor G and Fusidic Acid Inhibition

    Författare :Sebastian Hansson; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molekylär biofysik; Structure chemistry; Strukturkemi; Molecular biophysics; Biologi; Biology; Biomedicinska vetenskaper; Biomedical sciences; conformational change; fusidic acid; protein synthesis; elongation factor G; crystal structures;

    Sammanfattning : Elongation factor G (EF-G) catalyses the translocation step in protein synthesis on the ribosome. During this event the antibiotic Fusidic acid (FA) binds to and irreversably inhibits the release of the EF-G:GDP complex from the ribosome. LÄS MER

  3. 8. Torque and angle controlled tightening over the yield point of a screw

    Författare :Göran Toth; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; clevis; permanent elongation factor; Monte-Carlo simulations; bolted screwed joints; final preload; torque and angle controlled tightening; extreme-value method; plastic deformation; Taylor s series expansions; plastic spring constant of the screw; yield; elastic angle; momentary elongation factor; snug torque; torque controlled tightening; final torque; turn-of-nut method;

    Sammanfattning : .... LÄS MER

  4. 9. Characterizing Elongation of Protein Synthesis and Fusidic Acid Resistance in Bacteria

    Författare :Srihari Nagendra Ravi Kiran Koripella; Suparna Sanyal; Daniel Wilson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ribosome; Elongation factor-G; FusB; GTP; Staphylococcus aureus; Escherichia coli and Fusidic acid; Molecular Biology; Molekylärbiologi;

    Sammanfattning : Protein synthesis is a highly complex process executed by the ribosome in coordination with mRNA, tRNAs and translational protein factors. Several antibiotics are known to inhibit bacterial protein synthesis by either targeting the ribosome or the proteins factors involved in translation. LÄS MER

  5. 10. The ribosome, stringent factor and the bacterial stringent response

    Författare :Rose-Marie Jenvert; Lovisa Holmberg Schiavone; Suparna Sanyal; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ribosome; stringent factor; stringent response; tRNA; ribosomal protein L11; pppGpp; Cell biology; Cellbiologi; cellbiologi; Cellbiology;

    Sammanfattning : The stringent response plays a significant role in the survival of bacteria during different environmental conditions. It is activated by the binding of stringent factor (SF) to stalled ribosomes that have an unacylated tRNA in the ribosomal A-site which leads to the synthesis of (p)ppGpp. LÄS MER