Sökning: "Ectopic fat"

Visar resultat 6 - 10 av 18 avhandlingar innehållade orden Ectopic fat.

  1. 6. The role of growth factors in white fat browning and metabolic disease

    Författare :Carina Fischer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The adipose tissue is composed of a variety of cell types that constantly cross-communicate with each other to allow the tissue to operate and to adapt to various external stimuli. The diversity of these cell populations and their production of secretory factors define not only adipose tissue morphology, but also its function. LÄS MER

  3. 7. Regulation of Drosophila Jun by phosphorylation and the ubiquitin system during eye development

    Författare :Anders Isaksson; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Genetics; eye development; ubiquitin; D-Jun; phosphorylation; cytogenetics; Genetik; cytogenetik;

    Sammanfattning : The goal of these studies has been to elucidate the biological relevance of post-translational modifications in the context of a living organism. The model system used is photoreceptor differentiation during development of the compound eye in the fruit fly Drosophila melanogaster. LÄS MER

  4. 8. Protein kinase STK25 is a regulator of hepatic lipid partitioning and whole body metabolism

    Författare :Manoj Amrutkar; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NAFLD; NASH; Liver lipid metabolism; Type 2 diabetes; STK25;

    Sammanfattning : In past decade, type 2 diabetes (T2D) and associated metabolic complications have become a major global threat for human health with epidemic increase in incidence. Currently available treatments for T2D have several limitations and side effects making it difficult safely reach adequate metabolic control. LÄS MER

  5. 9. Morphological and functional effects of insulin signaling and the bHLH transcription factor Dimmed on different neuron types in Drosophila

    Författare :Yiting Liu; Dick R. Nässel; Irene Miguel-Aliaga; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; insulin signaling; Dimm; neuropeptide; insulin receptor; insulin-like peptide; drosophila; funktionell zoomorfologi; Functional Zoomorphology;

    Sammanfattning : In Drosophila, the insulin signaling pathway is at the interface between dietary conditions and control of growth and development, reproduction, stress responses and life span. Eight insulin like peptides (Dilp1-8), an insulin tyrosine kinase receptor (dInR) and its downstream components, as well as a relaxin-like receptor type (Lgr3) form the core of this signaling. LÄS MER

  7. 10. Mitochondria and its role in metabolic regulation and skeletal muscle function in healthy and disease conditions

    Författare :Zhengye Liu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Skeletal muscle function is critical for our overall health and to be able to perform daily activities. Skeletal muscle has the ability to adapt to various stimuli and mitochondria are known to play an important role in these adaptation processes. LÄS MER