Sökning: "Ectopic Fat"

Visar resultat 1 - 5 av 18 avhandlingar innehållade orden Ectopic Fat.

1. 1. Dietary Fatty Acids, Body Composition and Ectopic Fat : Results from Overfeeding Studies in Humans

   Författare :Fredrik Rosqvist; Ulf Risérus; Tommy Cederholm; Ian Macdonald; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Linoleic acid; Palmitic acid; SFA; PUFA; Fatty acids; Body composition; Liver fat; Ectopic fat; Adipose tissue; Medicinsk vetenskap; Medical Science;

   Sammanfattning : The aim of this thesis was to investigate the effects of dietary fatty acids on body composition and ectopic fat in humans, with emphasis on the role of the omega-6 polyunsaturated fatty acid (PUFA) linoleic acid (18:2n-6) and the saturated fatty acid (SFA) palmitic acid (16:0). The overall hypothesis was that linoleic acid would be beneficial compared with palmitic acid during overfeeding, as previously indicated in animals. LÄS MER

3. 2. Effects of diet intervention on body composition and ectopic fat accumulation in obese postmenopausal women

   Författare :Caroline Mellberg; Tommy Olsson; Mats Rudling; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; obesity; diet intervention; postmenopausal; ectopic fat; medicin; Medicine;

   Sammanfattning : Background Obesity is increasing worldwide and is a major contributor to morbidity and mortality. Notably, abdominal (central) obesity carries a high risk of obesity-related diseases, while peripheral fat accumulation can act in a protective manner. LÄS MER

4. 3. Lifestyle and glycaemic control before and after the onset of type 2 diabetes

   Författare :Robert Koivula; Genetisk och molekylär epidemiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 Diabetes; Prediabetes; Obesity; Beta-cell Function; Insulin Sensitivity; Physical Activity; Exercise; Diet; Lifestyle; Ectopic Fat; Genetic Epidemiology; Genetic Risk; Biomarker; Precision Medicine;

   Sammanfattning : Type 2 diabetes (T2D) is a complex disease with widespread physiological insults to the regulation of metabolic homeostasis, above all glycaemic regulation. The pathogenesis of T2D and its progression is broadly understood to be through a gradual decrease in peripheral insulin sensitivity, a compensatory rise in insulin secretion, and a gradual decline in beta-cell function, resulting in glycaemic dysregulation and eventual T2D. LÄS MER

5. 4. Metabolic consequences of a Paleolithic diet in obese postmenopausal women

   Författare :Caroline Blomquist; Tommy Olsson; Elin Chorell; Per-Arne Svensson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Postmenopausal women; Paleolithic diet; randomized diet intervention; fat metabolism; low-grade inflammation; circulating fatty acids; diet validation; obesity; insulin resistance; Postmenopausala kvinnor; Paleolitisk kost; randomiserad kostintervention; fettmetabolism; fetma; låggradig inflammation; cirkulerande fettsyror; kostvalidering; fetma; insulin resistens; medicin; Medicine;

   Sammanfattning : BackgroundObesity, in particular abdominal adiposity, is associated with elevated fatty acids and pro-inflammatory adipokines, which are linked to ectopic fat storage and insulin resistance. During menopause, there is a redistribution of fat from the peripheral to abdominal depots. LÄS MER

7. 5. Activation of the Cellular Immune Response in Drosophila melanogaster Larvae

   Författare :Ines Anderl; Dan Hultmark; Paul Badenhorst; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Drosophila melanogaster; immunity; blood cells; hematopoiesis; flow cytometry; in vivo imaging; genetic screens; Tl10b; fat body; Toll signaling; molekylärbiologi; Molecular Biology;

   Sammanfattning : During the last 40 years, Drosophila melanogaster has become an invaluable tool in understanding innate immunity. The innate immune system of Drosophila consists of a humoral and a cellular component. While many details are known about the humoral immune system, our knowledge about the cellular immune system is comparatively small. LÄS MER