Sökning: "ETV6 RUNX1-positive ALL"
Hittade 2 avhandlingar innehållade orden ETV6 RUNX1-positive ALL.
1. Genomic characterization of ETV6/RUNX1-positive acute lymphoblastic leukemia
Sammanfattning : The t(12;21) translocation generates the ETV6/RUNX1 fusion gene, present in 25% of childhood acute lymphoblastic leukemia. This fusion gene is important for leukemia development but is not sufficient for leukemia to arise. LÄS MER
2. Cancer proteogenomics : connecting genotype to molecular phenotype
Sammanfattning : The central dogma of molecular biology describes the one-way road from DNA to RNA and finally to protein. Yet, how this flow of information encoded in DNA as genes (genotype) is regulated in order to produce the observable traits of an individual (phenotype) remains unanswered. Recent advances in high-throughput data, i.e. LÄS MER
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