Sökning: "ESIMS oxygen adducts"

Hittade 2 avhandlingar innehållade orden ESIMS oxygen adducts.

  1. 1. Natural products from Bolivian plants and other sources

    Författare :Marcelo Bascope; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Växtbiokemi; Organic chemistry; Organisk kemi; Plant biochemistry; Bolivian plants; ESIMS oxygen adducts; Myrothecium roridum; Silphion persicum; Cyathea boliviana; Rheedia acuminata; Heliconia episcopalis; Iryanthera juruensis; Aniba canelilla; Natural products;

    Sammanfattning : The present research was focused on the phytochemical research of Bolivian plants; a) two medicinal ones Aniba canelilla and Iryanthera juruensis, both plants showed to have compounds with biological activity in different fields. Even though Aniba canelilla was studied before, new compounds were identified in this investigation. LÄS MER

  3. 2. Advances in analytical methodologies for studies of the platinum metallome in malignant cells exposed to cisplatin

    Författare :Yvonne Nygren; Erik Björn; Knut Irgum; Bente Gammelgaard; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Method development; Metallome; Inductively coupled plasma mass spectrometry; Electrospray ionization mass spectrometry; Liquid chromatography; Hyphenation; Organic modifier; Cisplatin; Platinum; Analytical chemistry; Analytisk kemi; analytisk kemi; Analytical Chemistry;

    Sammanfattning : The scientific progress about the important chemotherapeutic drug substance cisplatin (CDDP) and its function has often been rendered by data difficult to interpret, and still many questions about its mode of action remains to be clarified by the scientific community. However, studies of CDDP possess a high complexity due to; i) low intracellular concentration, ii) many potential biomolecule targets, iii) poor or unknown stability of the intact drug and its biomolecule adducts and iv) complex and varying sample matrices. LÄS MER