Sökning: "ESI-MS"

Visar resultat 6 - 10 av 83 avhandlingar innehållade ordet ESI-MS.

1. 6. Palladium-Catalyzed Carbonylation and Arylation Reactions

   Författare :Jonas Sävmarker; Mats Larhed; Gary Molander; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; palladium; carbonylation; styrene; amidine; aryl ketones; aryl sulfinates; ESI-MS; aryltrifluoroborates; Organic Pharmaceutical Chemistry; Organisk farmaceutisk kemi;

   Sammanfattning : Palladium-catalyzed reactions have found widespread use in contemporary organic chemistry due to their impressive range of functional group tolerance and high chemo- and regioselectivity. The pioneering contributions to the development of the Pd-catalyzed C-C bond forming cross-coupling reaction were rewarded with the Nobel Prize in Chemistry in 2010. LÄS MER

3. 7. Investigation of Modified Cellulose and Starch via Hydrolysis and Mass Spectrometry

   Författare :Arieh Cohen; Avdelningen för arbets- och miljömedicin; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ESI-MS; Polysaccharides; Hydrolysis; Cellulases; Starch Hydrolases; Enzymatic Degradation; Enzymes; Substituent Distribution; Modified Cellulose; Mass Spectrometry; Modified Starch; Analytical chemistry; Analytisk kemi; HPAEC-PAD;

   Sammanfattning : Starches and celluloses can be chemically modified in order to affect their physiochemical properties. Modification of these carbohydrate polymers entails derivatising their free hydroxyl groups with functional groups. LÄS MER

4. 8. Microfluidics in Surface Modified PDMS : Towards Miniaturized Diagnostic Tools

   Författare :Sara Thorslund; Fredrik Nikolajeff; Jonas Bergquist; Elisabeth Verpoorte; Uppsala universitet; []
   Nyckelord :Materials science; µTAS; micro total analysis system; PDMS; poly dimethylsiloxane ; microfluidics; heparin; blood filtration; on-chip; ESI-MS; desalting; QCM-D; biocompatible; CD4; capillary flow; lab-on-chip; microfabrication; enrichment; point-of-care; hydrophilic; oxidation; Materialvetenskap;

   Sammanfattning : There is a strong trend in fabricating miniaturized total analytical systems, µTAS, for various biochemical and cell biology applications. These miniaturized systems could e.g. gain better separation performances, be faster, consume less expensive reagents and be used for studies that are difficult to access in the macro world. LÄS MER

5. 9. Novel Metal-Mediated Organic Transformations : Focusing on Microwave Acceleration and the Oxidative Heck Reaction

   Författare :Per-Anders Enquist; Mats Larhed; Anders Hallberg; Troels Skrydstrup; Uppsala universitet; []
   Nyckelord :Organic chemistry; palladium II ; oxidative Heck reaction; high-throughput-chemistry; microwave acceleration; dicobalt octacarbonyl; in situ carbonylation; urea; diaryl ketones; ESI-MS; Organisk kemi;

   Sammanfattning : Transition metals have played an important role in synthetic organic chemistry for more than a century, and offer catalytic transformations that would have been impossible with classical chemistry. One of the most useful and versatile of the transition metals is palladium, which over the years has catalyzed many important carbon-carbon forming reactions. LÄS MER

7. 10. Palladium(II)-Catalyzed Heck Reactions : Domino Reactions, Decarboxylations, Mechanistic Studies & Continuous Flow Applications

   Författare :Ashkan Fardost; Mats Larhed; Patrick Guiry; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; palladium II ; dft; reaction mechanisms; esi-ms; heck; decarboxylation; microwave; continuous flow;

   Sammanfattning : This thesis describes research efforts dedicated to the development of palladium(II)-catalyzed oxidative Heck and Heck/Suzuki domino reactions, and the applications of a new microwave heating technology, purpose-built for continuous flow in organic synthesis.Paper I describes the development of a ligand-modulated approach for attaching aryl groups to a chelating vinyl ether. LÄS MER