Sökning: "ESI-MS"

Visar resultat 21 - 25 av 83 avhandlingar innehållade ordet ESI-MS.

1. 21. Development of Micro Liquid Separation Techniques using Electrospray Ionisation Mass Spectrometry in the Analysis of Polar Compounds and Proteins/Peptides

   Författare :Jenny Samskog; Elsa Lundanes; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; Analytisk kemi; Analytical chemistry; Analytisk kemi; Analytical Chemistry; Analytisk kemi;

   Sammanfattning : Electrospray ionisation (ESI) coupled to mass spectrometry (MS) is one of the most important detection techniques for chemical analysis of small drugs as well as large biomolecules in life science today. In this thesis, aspects on improved compatibility between liquid based separation systems and mass spectrometric detection were investigated regarding buffers, sample preparation and analysis of polar compounds as well as peptides and protein digests for enhanced ESI-MS performance. LÄS MER

3. 22. Microstructures for Chemical Analysis : Design, Fabrication and Characterisation

   Författare :Malin Svedberg; Fredrik Nikolajeff; Greger Thornell; Jan-Åke Schweitz; Sami Franssila; Uppsala universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Materials science; electrospray ionisation mass spectrometry; polymer microfabrication; paraffin actuators; hot embossing; Materialvetenskap; Materials science; Teknisk materialvetenskap;

   Sammanfattning : The interest for miniaturisation in chemical and biological analysis has increased in recent years. In this work, the design, fabrication and characterisation of tools for microanalysis have been studied. The focus is set on polymer microchips for applications in chemical analysis. LÄS MER

4. 23. On-line Electrochemistry Electrospray Ionisation Mass Spectrometry : Method Development and Applications

   Författare :Camilla Zettersten; Leif Nyholm; Per Sjöberg; Andries P. Bruins; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry; Kemi; Analytical Chemistry; analytisk kemi;

   Sammanfattning : This thesis deals with studies of on-line electrochemistry electrospray ionisation mass spectrometry (EC/ESI-MS). It is shown that the use of EC/ESI-MS demands optimal coupling characteristics. Pre-concentration and desalting, due to matrix exchange, were demonstrated for the model substance 1-hexanethiol in an EC/ESI-MS setup. LÄS MER

5. 24. Analysis of noncovalent and covalent protein-ligand complexes by electrospray ionisation mass spectrometry

   Författare :Gustav Sundqvist; Harry Brumer; Per Andrén; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; noncovalent complex; droplet fission; nano-electrospray ionisation; mass spectrometry; Analytical chemistry; Analytisk kemi;

   Sammanfattning : In this thesis, the application of electrospray ionisation mass spectrometry (ESI-MS) to the analysis of intact proteins is demonstrated. In papers I and II, the use of ESI-MS for the analysis of noncovalent protein-ligand complexes were discussed. LÄS MER

7. 25. New Mass Spectrometric Methods for Structure Analysis of Carboxymethyl Cellulose

   Författare :Jonas Enebro; Sigbritt Karlsson; Dane Momcilovic; Ulf Germgård; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; carboxymethyl cellulose; substituent distribution; rheology; enzyme hydrolysis; cellulase; permethylation; liquid chromatography; MALDI; ESI; mass spectrometry; Polymer chemistry; Polymerkemi;

   Sammanfattning : Carboxymethyl cellulose (CMC) is a cellulose derivative, made from cellulose by introduction of carboxymethyl groups along the molecules. The properties of CMC are affected by several parameters where the molar mass and molar mass distribution, degree of substitution (DS) and the distribution pattern along, and between, the cellulose molecules are the most prominent. LÄS MER