Sökning: "EROD"

Visar resultat 1 - 5 av 20 avhandlingar innehållade ordet EROD.

1. 1. Gill EROD Activity in Fish : A Biomarker for Waterborne Ah-receptor Agonists

   Författare :Alexandra Abrahamson; Ingvar Brandt; Björn Brunström; Janneche Utne Skaare; Uppsala universitet; []
   Nyckelord :Biology; biomarker; fish; gill; CYP1A; EROD; environmental monitoring; induction; inhibition; PAH; PCB; produced water; Biologi;

   Sammanfattning : Induction of the cytochrome P450(CYP)1A protein and the connected increase in 7-ethoxyresorufin O-deethylase (EROD) activity are common biomarkers in fish. Enhanced activity of this protein signals exposure to Ah-receptor agonists such as chlorinated dioxins, co-planar polychlorinated biphenyls (PCBs) and certain polycyclic aromatic hydrocarbons (PAHs). LÄS MER

3. 2. A Gill Filament EROD Assay : Development and Application in Environmental Monitoring

   Författare :Maria Jönsson; Ingvar Brandt; Björn Brunström; Kristian Ingebrigtsen; Håkan Olsén; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; aquatic; benzo[a]pyrene; biomarker; CYP1A; environmental monitoring; EROD; fish; gill; indigo; PCB; Biologi; Biology; Biologi;

   Sammanfattning : A gill filament-based assay for the cytochrome P450 1A (CYP1A)-catalysed activity ethoxyresorufin O-deethylase (EROD) was developed in rainbow trout (Oncorhynchus mykiss) and applied to Atlantic salmon (Salmo salar), Arctic charr (Salvelinus alpinus), Atlantic cod (Gadus morhua), saithe (Pollachius virens), and spotted wolffish (Anarhichas minor). Exposure to waterborne β-naphthoflavone (βNF; 10-6 M) induced branchial EROD activity in all species but the spotted wolffish. LÄS MER

4. 3. Evaluation of Biomarker Responses in Fish : with Special Emphasis on Gill EROD Activity

   Författare :Carin Andersson; Jan Örberg; Björn Brunström; Lars Förlin; Uppsala universitet; []
   Nyckelord :Biology; three-spined stickleback; biomarker; EROD; ethynylestradiol; gill; vitellogenin; spiggin; CYP1A inducers; humic substances; sperm quality; biomonitoring; Biologi;

   Sammanfattning : Many chemicals present in the aquatic environment can interfere with physiological functions in fish. Exposure to chemicals can be revealed by the use of biomarkers. Induction of 7-ethoxyresorufin O-deethylase (EROD) activity is a commonly used biomarker for exposure to CYP1A inducers such as dioxins and polyaromatic hyrdrocarbons. LÄS MER

5. 4. Azoles and Contaminants in Treated Effluents Interact with CYP1 and CYP19 in Fish

   Författare :Kristina Beijer; Ingvar Brandt; Björn Brunström; Henner Hollert; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Azole; fungicide; chemical; CYP1A; CYP19; EROD; aromatase; effluent; STP; wastewater; fish; stickleback; rainbow trout; Biologi med inriktning mot ekotoxikologi; Biology with specialization in Environmental Toxicology;

   Sammanfattning : Numerous contaminants are present in mixtures in the aquatic environment. Among these are the azoles, a group of chemicals that includes both pharmaceuticals and pesticides. Azole fungicides are designed to inhibit lanosterol 14-demethylase (cytochrome P450 (CYP) 51), while other azoles are intended to inhibit aromatase (CYP19), i.e. LÄS MER

7. 5. Biomarkers in perch (Perca fluviatilis) used in environmental monitoring of the Stockholm recipient and background areas in the Baltic Sea

   Författare :Tomas Hansson; Lennart Balk; Ulf Rannug; Tracy Collier; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biomarker; DDT; environmental monitoring; EROD; fish; GSI; nanoinjection; PAH; PCB; Perca fluviatilis; perch; reproduction; Environmental toxicology; Miljötoxikologi; Applied Environmental Science; tillämpad miljövetenskap;

   Sammanfattning : This thesis reports the results of biomarker measurements in three environmental monitoring projects. In the first project, which was part of the Swedish national environmental monitoring, biomarkers were measured annually in female perch (Perca fluviatilis) in two background areas in the Baltic Sea during 1988–2000, resulting in a unique 13-year series of measurements. LÄS MER