Sökning: "ERG rearrangement"

Hittade 2 avhandlingar innehållade orden ERG rearrangement.

1. 1. Assessing the ERG rearrangement for clinincal use in patients with prostrate cancer

   Författare :Maria Svensson; Ove Andrén; Swen-Olof Andersson; Fredrik Enlund; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; prognosis; biomarkers; ETS genes; ERG rearrangement; fluoroscence in situ hybridization; Medicine; Medicin;

   Sammanfattning : In Sweden, close to 10 000 men are annually diagnosed with prostate cancer (PCa) and approximately 2400 men die of their disease each year. Today there is no reliable marker that can separate patients who will have an aggressive type of disease that requires treatment, from patients who will have a more indolent clinical course and can be left untreated. LÄS MER

3. 2. Prognostic markers in pediatric leukemia and mechanisms of KRAS induced leukemogenesis

   Författare :Anna Staffas; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prognostic markers; AML; T-ALL; leukemia; FLT3; NPM1; ERG; BAALC; KRAS;

   Sammanfattning : Leukemia results from uncontrolled growth of genetically altered blood cells. Depending on the cell type of origin, the leukemia is defined as T-cell, B-cell, or myeloid and as acute or chronic depending on its characteristics. However, patients with a certain subtype of leukemia (e.g. LÄS MER