Sökning: "EMRE"
Hittade 5 avhandlingar innehållade ordet EMRE.
1. Resolving inflammation : analysis of mechanisms in relation to Alzheimer pathology and aging
Sammanfattning : Alzheimer’s disease (AD) is the most common type of dementia, and its clinical symptoms are the reflections of pathological changes in the brain. The main pathological features of AD are intracellular aggregates of hyper-phosphorylated tau protein and extracellular deposits of amyloid β (Aβ) peptide in amyloid plaques. LÄS MER
2. Microfluidic Compartmentalization for Smart Materials, Medical Diagnostics and Cell Therapy
Sammanfattning : The organisation of fluids in small compartments is ubiquitous in nature, such as in the cellular composition of all life. This work explores several engineering avenues where microscale fluid compartmentalization can bring novel material properties or novel functionality in life sciences or medicine. LÄS MER
3. Calibrating integration : studies on status, culture, knowledge and cooperation in acquisitions
Sammanfattning : Acquisitions represent a common modus operandi of firm growth. Notwithstanding their lasting popularity, the majority of deals are reported to be unsuccessful. Given their prevalence and practical relevance, acquisitions have attracted scholarly interest from diverse academic disciplines and traditions. LÄS MER
4. EmrE, a puzzling transporter : Assembly, biogenesis and evolution of a dual-topology membrane protein
Sammanfattning : Biological membranes are the key to cell existence, as they are able to both isolate and connect their interior with the environment. Membranes are composed of lipids and proteins that create a semi-permeable barrier; because the lipid bilayer stops free diffusion of most molecules and ions, membrane proteins play an important role in connecting the interior of the cell with its environment. LÄS MER
5. The Ins and Outs of Membrane Proteins : Topology Studies of Bacterial Membrane Proteins
Sammanfattning : α-helical membrane proteins comprise about a quarter of all proteins in a cell and carry out a wide variety of essential cellular functions. This thesis is focused on topology analyses of bacterial membrane proteins. The topology describes the two-dimensional structural arrangement of a protein relative to the membrane. LÄS MER