Sökning: "ECM proteins"

Visar resultat 1 - 5 av 78 avhandlingar innehållade orden ECM proteins.

  1. 1. Basement membrane components in the chondrocyte extracellular matrix

    Författare :Alexander Kvist; Lunds universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skelett; rheumatology locomotion; nidogen; chondroitin sulfate; collagen assembly; Skeleton; muscle system; type IV collagen; laminin; perlecan; basement membranes; ECM; chondrcytes; muskelsystem; reumatologi;

    Sammanfattning : The extracellular matrix (ECM) is a network of macromolecules which, together with cells, forms the various tissues of all metazoan organisms. Cartilage, in contrast to most other tissues, contains relatively few cells in proportion to the volume occupied by ECM. LÄS MER

  2. 2. Infection biology of the plant pathogenic fungus Bipolaris sorokiniana

    Författare :Dace Apoga; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; microscopy; Hordeum vulgare; barley; virulence; prehelminthosporol; phytotoxins; proteins; adhesion; fimbriae; extracellular matrix; Helminthosporium sativum; Cochliobolus sativus; Plant pathogenic fungi; Bipolaris sorokiniana; two-dimensional gel electrophoresis; mass spectrometry; gas chromatography; Ecology; Ekologi;

    Sammanfattning : Bipolaris sorokiniana is a fungal pathogen causing severe disease mainly in wheat and barley worldwide. In this thesis two aspects of the infection process were investigated: the adhesion mechanism of the fungus and the role of the non-host specific phytotoxin prehelminthosporol (PHL) in the disease. Adhesion of B. LÄS MER

  3. 3. Complex Formation in the Extra Cellular Matrix- Structural Study of CTLD of Agrrecan, Tenascin-R and Chondroadherin

    Författare :Anna Pramhed; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; aggrecan; ECM; fibulin; structure; tenascin; CHAD; chondroadherin; X-ray; crystallography; calcium; CTLD; C-type lectin; fibronectin; FnIII; LRR; epidermal growth factor; leucine-rich repeat; matrix; EGF; cbEGF;

    Sammanfattning : The cells of higher organisms exist in a complex protein network, the extracellular matrix (ECM), which has a wide variety of different components such as glycoproteins, proteoglycans and carbohydrates. As well as being the physical scaffold on which the cells are dependent for their positioning and mobility, the ECM exercises control over the cells, and changes in the matrix will affect the adhesion, proliferation and differentiation properties of these cells. LÄS MER

  4. 4. Studies on chondroadherin-an extracellular matrix leucine-rich repeat protein

    Författare :Christina Wenglén; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk biologi; Clinical biology; COMP; SLRP; ECM; collagen; cartilage; chondroadherin;

    Sammanfattning : This thesis describes chondroadherin, one of the leucine-rich repeat proteins in the extracellular matrix (ECM) of cartilage. Chondroadherin defines a subgroup of its own by not having an N-terminal extension, having a different cysteine pattern and by being devoid of carbohydrate substitutions. LÄS MER

  5. 5. Cartilage homeostasis: Modulation of cells and extracelllar matrix assembly

    Författare :Anna Johnson; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine human and vertebrates ; COMP; Perlecan; chondroadherin; cartilage; ECM; Medicin människa och djur ;

    Sammanfattning : The cartilage extracellular matrix consists of the collagen network which enmeshes the large aggregating proteoglycan, aggrecan. Accessory molecules regulate the formation and maintenance of these structures. This thesis studies aspects of cartilage assembly during development and its degradation in disease, focusing on the collagen network. LÄS MER