Sökning: "EBP"
Visar resultat 6 - 10 av 56 avhandlingar innehållade ordet EBP.
6. Alzheimer Aβ peptides induce dysregulation of C/EBP and NF-кB in glial cells
Sammanfattning : Inflammation is believed to contribute to neurodegeneration in Alzheimer’s disease (AD). AD in turn is believed to be a consequence of accumulated amyloid-β (Aβ) peptides, that subsequently form senile plaques, due to imbalance between production and clearance of Aβ. LÄS MER
7. C/EBP transcription factors in lung cellular differentiation and development
Sammanfattning : During embryonic development the lung is lined with a primitive epithelium. As development proceeds, the epithelium matures and differentiates into several cell types that together with cells of mesenchymal origin constitute the adult lung. LÄS MER
8. Studies of the C/EBP family of transcription factors : cloning, regulation, and expression
Sammanfattning : The CCAAT/Enhancer Binding Protein (C/EBP) family belongs to the basic leucine zipper class of transcription factors with a total of 6 members having been identified in this family so far. This gene family has been mainly implicated in regulation of cell specific gene expression and differentiation. LÄS MER
9. Transcriptional regulation of differentiation markers in the distal lung epithelium : a role for C/EBP factors
Sammanfattning : Late lung development is characterised by extensive cellular differentiation, resulting in a variety of specialised epithelial cell types. Although much is known of the extracellular signalling involved in lung morphogenesis, less is currently known of the intracellular developmental mechanisms that govern cellular differentiation. LÄS MER
10. Regulation of gene expression in pulmonary inflammation and differentiation : a role for C/EBP transcription factors
Sammanfattning : CCAAT/enhancer-binding protein (C/EBP) transcription factors play essential roles in gene regulation. The lung-enriched isoform C/EBPα is known to inhibit proliferation, promote differentiation and stimulate gene expression characteristic of the mature differentiated pulmonary epithelium. LÄS MER