Sökning: "E6"
Visar resultat 1 - 5 av 45 avhandlingar innehållade ordet E6.
1. Genetic Risk Factors for Cervical Carcinoma in situ
Sammanfattning : Oncogenic human papillomaviruses (HPVs) are implicated in 99.7 % of cervical cancer cases but require the co-operation of other factors. To investigate potential genetic risk factors we have typed the HLA class II DRB1 and DQB1 loci in 478 women diagnosed with cervical carcinoma in situ and in 608 age-matched controls. LÄS MER
2. The balance of splicing : A novel insight into the splicing regulation of high-risk HPV E6 and E7 oncogenes
Sammanfattning : HPV is associated with several cancers. The genome consists of a long control region, early (E1, E2, E4, E5, E6 and E7) and late (L1 and L2) genes. The E6 and E7 proteins prevent cells from entering apoptosis and regulate the cell cycle. A deregulated expression of these can result in malignant transformations. LÄS MER
3. Regulation of human papillomavirus 16 gene expression at the level of mRNA processing
Sammanfattning : .... LÄS MER
4. Cervical dysplasia and cervical cancer in pregnancy: diagnosis and outcome
Sammanfattning : ABSTRACT:Cervical cancer is one of the most common types of cancer that is diagnosed during pregnancy. The primary aim in investigation of atypical cervical cytology during pregnancy is to exclude cancer so that further treatment of the lesion can be postponed until after delivery. LÄS MER
5. Regulation of HPV16 Early Gene Expression
Sammanfattning : Human papillomavirus type 16 (HPV16) is the most common high-risk type and isassociated with more than 50% cervical cancer cases as well as a number of headand neck cancer cases. The life cycle of HPV16 is strictly linked to celldifferentiation in the squamous epithelium with expression of the HPV16 earlygenes. LÄS MER