Sökning: "Drosophila"

Visar resultat 16 - 20 av 306 avhandlingar innehållade ordet Drosophila.

  1. 16. Genetic dissection of tubulogenesis in the Drosophila trachea

    Författare :Johanna Hemphälä; Christos Samakovlis; Reinhard Schuh; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Drosophila; trachea; transposon mutagenesis screen; fusion; Dpp; Delta; tubular dimensions; Grainyhead; Krotzkopf verkehrt; intralumenal matrix; Developmental biology; Utvecklingsbiologi;

    Sammanfattning : The formation of branched tubular organs, such as the mammalian lung kidney and vascular system, is an essential process in animal development. The Drosophila tracheal (respiratory) system provides a genetic model system to study the highly ordered process of branch outgrowth and fusion required to form continuous tubular networks. LÄS MER

  2. 17. Chromatin regulators and transcriptional control of Drosophila development

    Författare :Qi Dai; Mattias Mannervik; Albert J. Courey; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chromatin; Co-factors; Transcription; Development; Drosophila; Developmental biology; Utvecklingsbiologi; Developmental Biology; miljömedicinsk utvecklingsbiologi;

    Sammanfattning : The development of a multicellular organism is programmed by complex patterns of gene expression. In eukaryotic cells, genes are packaged by histone proteins into chromatin. Chromatin regulators often function as transcription co-factors. LÄS MER

  3. 18. Sexual Conflict and Gene Expression in Drosophila melanogaster

    Författare :Paolo Innocenti; Edward Morrow; Göran Arnqvist; Andrew G Clark; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Sexual conflict; sexual selection; male-female coevolution; gene expression; transcriptome; microarrays; sexual dimorphism; Drosophila; Biology; Biologi; Biologi med inriktning mot zooekologi; Biology with specialization in Animal Ecology; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Sammanfattning : Sexual conflict is broadly defined as a conflict between the evolutionary interests of the two sexes. Depending on the genetic architecture of the traits involved, it can occur at the level of male-female interactions or take the form of selection acting to change the mean of a shared trait against the sign of its genetic correlation. LÄS MER

  4. 19. A Drosophila Disease-Model for Transthyretin-associated Amyloidosis

    Författare :Malgorzata Pokrzywa; Erik Lundgren; Damian Crowther; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; transthyretin; amyloid; amyloidosis; Drosophila; transthyretin-associated amyloidosis; Familial amyloid polyneuropathy; neurodegeneration; serum amyloid P component; Non-steroidal Anti-Inflammatory Drugs; drug screens; Molecular biology; Molekylärbiologi;

    Sammanfattning : Amyloidoses comprise a group of gain-of-toxic function protein misfolding diseases, in which normally soluble proteins in their functional state undergo conformational changes into highly organized and generally intractable thread-like aggregates, termed amyloid fibrils. These structures accumulate predominantly in the extracellular space but growing evidence suggests that amyloids may start to form intracellularly. LÄS MER

  5. 20. Interaction Between Drosophila melanogaster mbn-2 Cells and Bacteria

    Författare :Karin Johansson; Kenneth Söderhäll; Lage Cerenius; Martin Bilej; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell biology; Drosophila; innate immunity; bacteria; host - pathogen interaction; Cellbiologi; Cell biology; Cellbiologi;

    Sammanfattning : Innate immunity relies on a repertoire of germline-encoded non-rearranging pattern recognition receptors that bind to invariant microbial surface molecules. This event initiates a number of signal transduction cascades that lead to humoral and cellular defense responses like synthesis of antimicrobial peptides, phagocytosis and coagulation – mechanisms that efficiently fight infectious microorganisms and have been evolutionary conserved to exist in parallel with the antibody-based adaptive immunity found in vertebrates. LÄS MER