Sökning: "Dose-Response Relationship"
Visar resultat 6 - 10 av 111 avhandlingar innehållade orden Dose-Response Relationship.
6. Clinical and experimental studies in corticosteroid contact allergy
Sammanfattning : Corticosteroids are anti-inflammatory and anti-proliferative substances that also can induce sensitization, mainly through skin contact. In a sensitized individual, it can be hard to disclose the contact allergy at patch testing because the anti-inflammatory effect may mask the allergic contact reaction. LÄS MER
7. Microdosimetric description of beam quality and biological effectiveness in radiation therapy
Sammanfattning : .... LÄS MER
8. Bone and kidney effects from cadmium exposure : dose effect and dose response relationships
Sammanfattning : Cadmium is a heavy metal that has been dispersed in the environment during the last century due to human activity. It is well known that high cadmium exposure causes renal damage and in severe cases also osteoporosis and osteomalacia. Osteoporosis is a major cause of morbidity worldwide. LÄS MER
9. Estimation and optimal designs for multi-response Emax models
Sammanfattning : This thesis concerns optimal designs and estimation approaches for a class of nonlinear dose response models, namely multi-response Emax models. These models describe the relationship between the dose of a drug and two or more efficacy and/or safety variables. LÄS MER
10. Transcriptional biomarkers of toxicity – powerful tools or random noise? : An applied perspective from studies on bivalves
Sammanfattning : Aquatic organisms are constantly at risk of being exposed to potentially harmful chemical compounds of natural or anthropogenic origin. Biological life can for instance respond to chemical stressors by changes in gene expression, and thus, certain gene transcripts can potentially function as biomarkers, i.e. LÄS MER