Sökning: "Dose homogeneity"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden Dose homogeneity.

  1. 1. New Concepts in Administration of Drugs in Tablet Form : Formulation and Evaluation of a Sublingual Tablet for Rapid Absorption, and Presentation of an Individualised Dose Administration System

    Författare :Susanne Bredenberg; Christer Nyström; Carla Caramella; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; Interactive mixture; Dose homogeneity; Disintegration; Bioadhesion; Oromucosal delivery; Sublingual tablet; Rapid absorption; Individual dosage; Drug dispensing device; Galenisk farmaci; Pharmaceutics; Galenisk farmaci; galenisk farmaci; Pharmaceutics;

    Sammanfattning : This thesis presents two new concepts in oral drug administration and the results of evaluation of some relevant formulation factors.Investigation into improving the homogeneity of mixtures for tableting indicated that it may be possible to obtain interactive dry mixtures of micronised drugs containing drug proportions as low as 0.015% w/w. LÄS MER

  3. 2. Radiotherapy in a FLASH : Towards clinical translation of ultra-high dose rate electron therapy

    Författare :Elise Konradsson; Lund Medicinsk strålningsfysik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Radiotherapy; Dosimetry; Ultra-high dose rate; Electron therapy; FLASH; Fysicumarkivet A:2023:Konradsson;

    Sammanfattning : FLASH radiotherapy (FLASH-RT) is a promising new approach to radiotherapy that has the potential to transform the field. By administering radiation at ultra-high dose rates (UHDR) on a millisecond timescale, FLASH-RT may increase normal tissue tolerance compared to conventional radiotherapy while maintaining the anti-tumoral effect. LÄS MER

  4. 3. Radiation burden from modern radiation therapy techniques including proton therapy for breast cancer treatment - clinical implications

    Författare :Anna M. Flejmer; Alexandru Dasu; Gunnar Adell; Olle Stål; Margaretha Stenmarker; Thomas Björk-Eriksson; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : The purpose of this thesis was to study the clinical implications of modern radiotherapy techniques for breast cancer treatment. This was investigated in several individual studies. LÄS MER

  5. 4. Quality assurance for magnetic resonance imaging (MRI) in radiotherapy

    Författare :Mary Adjeiwaah; Tufve Nyholm; Rob HN Tijssen; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Magnetic resonance imaging; Radiotherapy; geometric distortions; patient-induced susceptibilities MR-only; radiofysik; radiation physics;

    Sammanfattning : Magnetic resonance imaging (MRI) utilizes the magnetic properties of tissues to generate image-forming signals. MRI has exquisite soft-tissue contrast and since tumors are mainly soft-tissues, it offers improved delineation of the target volume and nearby organs at risk. LÄS MER

  7. 5. Image Analysis for Trabecular Bone Properties on Cone-Beam CT Data

    Författare :Eva Klintström; Örjan Smedby; Rodrigo Moren; Torkel Brismar; Dan Mellström; Linköpings universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : Trabecular bone structure as well as bone mineral density (BMD) have impact on the biomechanical competence of bone. In osteoporosis-related fractures, there have been shown to exist disconnections in the trabecular network as well as low bone mineral density. Imaging of bone parameters is therefore of importance in detecting osteoporosis. LÄS MER