Sökning: "Dora Hancz"

Hittade 1 avhandling innehållade orden Dora Hancz.

  1. 1. Regulation of inflammasomes by host- and pathogen-derived factors

    Författare :Dora Hancz; Värd-patogeninteraktioner; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Innate Immunity; pattern recognition receptors; inflammasome; Streptococcus pyogenes;

    Sammanfattning : The term inflammasome was first coined in 2002 and describes an intracellular multiprotein complex mediating inflammation by inducing the release of pro-inflammatory cytokines (IL-1β and IL-18) and a lytic form of cell death called pyroptosis. Since then, an impressive amount of research has revealed many details about the mechanisms of inflammasome activation as well as the functional relevance of inflammasome activation in different contexts. LÄS MER