Sökning: "Display"

Visar resultat 11 - 15 av 1442 avhandlingar innehållade ordet Display.

1. 11. Discovery of targets for tumor immunotherapy using phage display technology

   Författare :Jesper Tordsson; Immunologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; serology; Immunology; colon cancer; melanoma; tumor immunotherapy; phage display; scFv; Immunologi; serologi; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

   Sammanfattning : This thesis has focused on the development of methods and their applications for the identification of antibodies reactive with tumor associated antigens (TAA). The phage display technology provides a powerful mean to generate antibodies potentially useful for tumor immunotherapy. LÄS MER

3. 12. Staging the world. Rome and the other in the triumphal procession

   Författare :Ida Östenberg; Antikens kultur och samhällsliv; []
   Nyckelord :HUMANIORA; HUMANITIES; world mastery; kings; barbarians; conquest; aerarium; wealth; triumphator; representations; captives; spoils; enargeia; spectators; display; role-playing; processional sequence; self-definition; the other; ritual; performance; Rome; triumphal procession; oikumene.; Ancient history; Antikens och forntidens historia;

   Sammanfattning : The triumphal procession staged Roman conquest and supremacy, featuring the defeated ‘other’ as opposed to the victorious ‘self’ in a rather fixed role-playing. This thesis takes as its theoretical premise that these ritually recurrent and visually emphatic processions both conveyed and constructed Roman views of the self and the other, and that they can be studied as formative expressions of such conceptions. LÄS MER

4. 13. Interaction engineered three-helix bundle domains for protein recovery and detection

   Författare :Tove Alm; Sophia Hober; Rainer Hahn; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; ABD; Zbasic; albumin; protein engineering; phage display; staphylococcal display; inclusion bodies; refolding; proteomics; orthogonal affinity purification; Bioengineering; Bioteknik; Immunology engineering; Immunteknik;

   Sammanfattning : HTML clipboard The great advances in DNA technology, e.g. sequencing and recombinant DNA techniques, have given us the genetic information and the tools needed to effectively produce recombinant proteins. Recombinant proteins are valuable means in biotechnological applications and are also emerging as alternatives in therapeutic applications. LÄS MER

5. 14. An albumin-binding domain as a scaffold for bispecific affinity proteins

   Författare :Johan Nilvebrant; Sophia Hober; Andrew Bradbury; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; albumin-binding domain; bispecific; albumin; affinity protein; phage display; staphylococcal display; orthogonal affinity purification; TNF-alpha; ErbB2; ErbB3; SRA - Molecular Bioscience; SRA - Molekylär biovetenskap;

   Sammanfattning : Protein engineering and in vitro selection systems are powerful methods to generate binding proteins. In nature, antibodies are the primary affinity proteins and their usefulness has led to a widespread use both in basic and applied research. LÄS MER

7. 15. Engineering strategies for ABD-derived affinity proteins for therapeutic and diagnostic applications

   Författare :Mikael Åstrand; Sophia Hober; John Löfblom; Larry Gold; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ABD; ADAPT; Protein G; ERBB2; ERBB3; Directed evolution; phage display; staphylococcal display; bispecific; Bioteknologi; Biotechnology;

   Sammanfattning : Small stable protein domains are attractive scaffolds for engineering affinity proteins due to their high tolerance to mutagenesis without loosing structural integrity. The albuminbinding domain is a 5 kDa three-helix bundle derived from the bacterial receptor Protein G with low-nanomolar affinity to albumin. LÄS MER