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Visar resultat 1 - 5 av 9547 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Crohn's disease : Studies on epidemiology, twins, aetiological factors and clinical course with special reference to smoking

   Författare :Eva Lindberg; Linköpings universitet; []
   Nyckelord :Crohn s disease; epidemiology; incidence; prevalence; smoking; genetics; twins; dietary antigens; yeast; Saccharomyces cerevisiae; mannan; gliadin; betalactoglobulin; ovalbuntin; MEDICINE; MEDICIN;

   Sammanfattning : In an epidemiological study of the incidence of Crohn's disease in Orebro county during the 25-year period 1963-1987, the mean annual incidence was 6.1/105 inhabitants. During the first five year period the mean incidence was 4.3 but during the following four quinquennia the incidence was stable at around 6. LÄS MER

3. 2. Chrohn's disease : aspects of epidemiology, clinical course, and faecal calprotectin

   Författare :Yaroslava Zhulina; Jonas Halfvarson; Curt Tysk; Hans Strid; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Crohn’s disease; epidemiology; faecal calprotectin; Medicine; Medicin;

   Sammanfattning : The overall aim of this thesis was to study epidemiological and clinical changes in the natural history of Crohn’s disease, its phenotype, the need for surgery and pharmacological therapy over time, as well as the role of faecal calprotectin as a biomarker of pathophysiology and disease course.An increased incidence and prevalence of Crohn’s disease was seen in the period 1963-2010. LÄS MER

4. 3. Coeliac disease : Clinical and immunological aspects

   Författare :Tony Hansson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Coeliac disease; cytokines; TGF-beta; tissue transglutaminase; IL-4; IFN-gamma; TNF-alpha; ELISPOT; anti-endomysiumantibodies; anti-gliadin antibodies; Onkologi; Oncology; Onkologi; Klinisk immunologi; Clinical Immunology;

   Sammanfattning : A better immunological definition of coeliac disease and highly discriminatory serum markers are needed to identify children with early mucosal lesions and for rapid follow-up and a better knowledge of antigen reactivity and cytokine production will be needed to clarify the pathogenic mechanisms.The numbers of circulating IgAanti-gliadin antibody-producing (IgAAGA SFC) cells were increased in patients with untreated coeliac disease compared to controls and treated coeliac disease patients. LÄS MER

5. 4. Gallstone disease : Population based studies on risk factors, symptomatology and complications

   Författare :Ingvar Halldestam; Kurt Borch; Lars Granström; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epidemiology; gallstone disease; symptomatology; complications; risk factors; Surgical research; Kirurgisk forskning;

   Sammanfattning : Background & aims: Gallstone disease is common, costly and its complications are sometimes life threatening. The aim of this thesis is to determine the prevalence and incidence in relation to putative risk factors in the general population. LÄS MER

7. 5. Parkinson’s disease : the prodromal phase and consequences with respect to working life

   Författare :Helena Nyström; Anna Nordström; Peter Nordström; Kristian Winge; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson’s disease; quality of life; employment; rehabilitation; prodromal phase; risk markers; depression; muscle strength; injurious fall; epidemiology;

   Sammanfattning : Background: Parkinson’s disease (PD) is a common, progressive neurodegenerative disorder, recognized by the motor symptoms of bradykinesia, tremor, rigidity, and postural impairment. At clinical onset, extensive amounts of dopaminergic neurons have already been lost. LÄS MER