Sökning: "Disease prediction"

Visar resultat 1 - 5 av 368 avhandlingar innehållade orden Disease prediction.

1. 1. Prediction of Alzheimer’s disease in subjects with Mild Cognitive Impairment using biomarkers

   Författare :Peder Buchhave; Klinisk minnesforskning; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; Mild Cognitive Impairment; Biomarkers; Prediction; Cerebrospinal fluid; Amyloid.;

   Sammanfattning : Background: Alzheimer’s disease (AD) is the most common cause of dementia. In order to have effect of future disease-modifying therapies for AD, the disease must be identified early, before the patients have developed dementia. Many patients with Mild Cognitive Impairment (MCI) have prodromal AD, but other causes for the syndrome are common. LÄS MER

3. 2. Carotid artery disease : plaque features and vulnerability

   Författare :Fisnik Jashari; Michael Henein; Per Wester; Christine Kremer; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Carotid atherosclerosis; ultrasound; plaque features; echogenicity; calcification; surface plaque irregularities; subclinical atherosclerosis; cerebrovascular symptoms; Cardiology; kardiologi; cardiovascular disease; hjärt- och kärlforskning;

   Sammanfattning : Background: Atherosclerosis is an important cause of stroke. Ultrasound offers the convenience of real-time and detailed assessment of carotid plaque features as well as arterial wall thickening and composition. LÄS MER

4. 3. Functional association networks for disease gene prediction

   Författare :Dimitri Guala; Erik L L Sonnhammer; Hjalmar Brismar; Yves Moreau; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; network biology; biological networks; network prediction; functional association; functional coupling; network integration; functional association networks; genome-wide association networks; gene networks; protein networks; fret; functional enrichment analysis; network cross-talk; pathway annotation; gene prioritisation; network-based gene prioritization; benchmarking; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

   Sammanfattning : Mapping of the human genome has been instrumental in understanding diseasescaused by changes in single genes. However, disease mechanisms involvingmultiple genes have proven to be much more elusive. Their complexityemerges from interactions of intracellular molecules and makes them immuneto the traditional reductionist approach. LÄS MER

5. 4. Prevalence and Prognostic Impact of Periodontal Disease and Conventional Risk Factors in Patients with Stable Coronary Heart Disease

   Författare :Ola Vedin; Claes Held; Emil Hagström; Bertil Lindahl; Mai-Lis Hellenius; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Coronary heart disease; Secondary prevention; Prevention; Periodontal Disease; Tooth loss; Risk prediction; Risk factors; Myocardial infarction; Kardiologi; Cardiology;

   Sammanfattning : The purpose of this thesis was to assess the prevalence and management of established cardiovascular (CV) risk factors and the prevalence and influence of self-reported markers (number of teeth and frequency of gum bleeding) of periodontal disease (PD), a less explored CV risk factor, in patients with stable chronic coronary heart disease (CHD).We studied patients from the global STabilization of Atherosclerotic plaque By Initiation of darapLadIb TherapY (STABILITY) trial (n=15,828), in which patients with stable chronic CHD were randomized to either darapladib or placebo. LÄS MER

7. 5. Population-based prediction of atrial fibrillation

   Författare :Gustav Smith; Kardiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atrial fibrillation; prediction; epidemiology; genetics; natriuretic peptide; heart failure;

   Sammanfattning : Background: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and increases in prevalence. As AF confers increased risk of morbidity, stroke, dementia and mortality, a major objective of cardiovascular epidemiology today is the development of tools for prediction and prevention of AF and its consequences. LÄS MER