Sökning: "Dimitrios Makrygiannakis"

Hittade 1 avhandling innehållade orden Dimitrios Makrygiannakis.

1. 1. Post-translational and therapy-induced modifications in rheumatoid arthritis

   Författare :Dimitrios Makrygiannakis; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovial proliferation and excessive mononuclear infiltration leading to destruction of bone and cartilage, with subsequent joint deformities and physical disability. Even though RA etiology is still unknown, autoantibody driven pathogenic mechanisms are considered to be important, with strong evidence for the pathogenic potentials of antibodies directed against citrullinated antigens. LÄS MER