Sökning: "Diffuse Axonal Injury"
Visar resultat 1 - 5 av 10 avhandlingar innehållade orden Diffuse Axonal Injury.
1. Modelling of Diffuse Brain Injury: Combining Methods to Study Possible Links between Transient Intracranial Pressure and Injury
Sammanfattning : The objectives of this research are the study of sagittal rotational acceleration induced diffuse brain injury mechanisms. Such injuries are common in vehicle accidents in particular; the consequences range from mild to severe symptoms and may lead to persistent neurological dysfunction. LÄS MER
2. Clinical Consequences of Axonal Injury in Traumatic Brain Injury
Sammanfattning : Traumatic brain injury (TBI), mainly caused by road-traffic accidents and falls, is a leading cause of mortality. Survivors often display debilitating motor, sensory and cognitive symptoms, leading to reduced quality of life and a profound economic burden to society. LÄS MER
3. Oligodendrocyte pathology following Traumatic Brain Injury : Experimental and clinical studies
Sammanfattning : Traumatic brain injury (TBI) caused by traffic and fall accidents, sports-related injuries and violence commonly results in life-changing disabilities. Cognitive impairments following TBI may be due to disruption of axons, stretched by the acceleration/deceleration forces of the initial impact, and their surrounding myelin in neuronal networks. LÄS MER
4. Assessment of experimental neurotrauma
Sammanfattning : Model systems of closed head injury are designed to replicate aspects of traumatic brain injury, ischemia and epilepsy in man. The aim of this thesis was to (1) develop sensitive systems enabling analyses of the biochemical reactions, as reflected by leakage of marker compounds to the cerebrospinal fluid (CSF); and (2) develop and assess a new model for closed head injury and associated dynamic changes in the brain cell. LÄS MER
5. Cellular Reactions and Behavioral Changes in Focal and Diffuse Traumatic Brain Injury : A Study in the Rat and Mouse
Sammanfattning : Traumatic brain injury (TBI) is a severe condition and a major cause of death and disability. There is no pharmacological treatment available in clinical practice today and knowledge of brain injury mechanisms is of importance for development of neuroprotective drugs. LÄS MER