Sökning: "Diarrhoeal disease"
Visar resultat 1 - 5 av 11 avhandlingar innehållade orden Diarrhoeal disease.
1. Genetic diversity of the heat labile (LT) and heat stable (ST) toxins of human enterotoxigenic Escherichia coli (ETEC): New insights into polymorphism, regulation, and gene transcription
Sammanfattning : Infection with enterotoxigenic Escherichia coli (ETEC) is a leading cause of diarrhea in children in developing countries and travelers to endemic regions. ETEC is a diverse pathogen, with a wide range of virulence factors including enterotoxins and more than 25 identified colonization factors (CFs). LÄS MER
2. Diarrhoeal diseases in low- and middle-income countries : trends, management and control
Sammanfattning : Background: Diarrhoeal diseases constitute a major disease burden on children in low- and middle-income countries (LMC), with an estimated 2 million 0-4 years old dying annually due to diarrhoea. Dehydration is the main cause of these deaths. An oral remedy based on glucose and sodium to treat dehydration was developed in the 1960s. LÄS MER
3. Cryptosporidium infection in dairy cattle : prevalence, species distribution and associated management factors
Sammanfattning : For almost 25 years, it has been known that Cryptosporidium parasites infect Swedish calves. This thesis explores how common these parasites are at herd level and at individual level in preweaned calves, young stock and periparturient cows. Species distribution and association with diarrhoeal problems are also highlighted. LÄS MER
4. The enteric nervous sytem and infectious diarrhoea. An experimental study in mouse and rat
Sammanfattning : Aim: To evaluate the role of the enteric nervous system in one of the most common types of infectious diarrhoea worldwide, rotavirus infection, and to further clarify the mechanisms behind neurally mediated intestinal secretion. Methods: The experiments were performed on neonatal and adult mice and adult rats. Experimental setups: In vitro: 1. LÄS MER
5. Modulators of Vibrio cholerae predator interaction and virulence
Sammanfattning : Vibrio cholerae, the causal agent of cholera typically encodes two critical virulence factors: cholera toxin (CT), which is primarily responsible for the diarrhoeal purge, and toxin-co-regulated pilus (TCP), an essential colonisation factor. Nontoxigenic strains expressing TCP can efficiently acquire the CT gene through lysogenic conversion with CTXΦ, a filamentous phage that encodes CT and uses TCP as a receptor. LÄS MER