Sökning: "Diabetes och celiaki"
Visar resultat 16 - 20 av 27 avhandlingar innehållade orden Diabetes och celiaki.
16. Lipid metabolism in the pancreatic beta-cell. Implications for insulin secretion
Sammanfattning : We have investigated the role of lipid metabolism with regard to beta-cell function and insulin secretion. Lipids are known to play a crucial functional role in the pancreatic beta-cell, where they are essential for adequate hormone release, but may also exert a long-term toxic effect, leading to beta-cell dysfunction. LÄS MER
17. Beta cell function in autoimmune diabetes in young adults
Sammanfattning : This thesis presents the results from a study of the first four years of diabetes in 879 patients aged 15-34 years at diagnosis. The aims of this study were to compare clinical classification with the presence of autoantibodies, to study the natural course of beta cell function during the first years of disease and to define predictive factors for the remaining beta cell function after diagnosis. LÄS MER
18. Helicobacter pylori cell surface interactions with glycosaminoglycans. Identification and characterisation of proteins binding to heparin/heparan sulphate
Sammanfattning : Helicobacter pylori is a gastric pathogen which cause chronic type B gastritis and peptic ulcer disease. H. pylori produces virulence factors such as urease, vacuolating cytotoxin VacA, cag pathogenicity island-associated proteins, flagella and adhesins. LÄS MER
19. Early life dietary factors on the risk of celiac disease. Associations of dietary factors with risk of celiac disease in children at genetic risk
Sammanfattning : .... LÄS MER
20. Searching for Celiac Disease Screening-detected celiac disease in an HLA-genotyped birth cohort
Sammanfattning : Objectives: Celiac disease is a common immune mediated enteropathy strongly associated with HLA-DQB1*02 (DQ2), *0302 (DQ8), or both and the presence of tissue transglutaminase autoantibodies (tTGA). Prevalence studies have revealed that most affected individuals go undetected because of subclinical signs or being asymptomatic rendering screening a method for identification. LÄS MER