Sökning: "Developmental Immunology"

Visar resultat 1 - 5 av 13 avhandlingar innehållade orden Developmental Immunology.

  1. 1. Identification of candidate genes involved in Mercury Toxicokinetics and Mercury Induced Autoimmunity

    Författare :Hammoudi Alkaissi; Per Hultman; Said Havarinasab; Peter Söderkvist; Jesper Bo Nielsen; Johan Rönnelid; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : BACKGROUND: Autoimmune diseases require the involvement and activation of immune cells and occur when the body builds up an immune response against its own tissues. This process takes place due to the inability to distinguish self-antigen from foreign antigen. Systemic autoimmunity represents an important cause of morbidity and mortality in humans. LÄS MER

  3. 2. The Drosophila POU/Oct factors: multifaceted proteins

    Författare :Priya Gohel; Ylva Engström; Mariana Wolfner; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; POU Oct factors; transcriptional regulation; innate immunity; developmental processes; mitotic spindles; chromosome segregation; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Dysregulation of physiological and cellular processes underlies various pathological conditions, including cancer and inflammatory disorders. Unraveling the molecular mechanisms driving these processes is crucial. LÄS MER

  4. 3. Identification and characterization of progenitor populations in the human adult heart

    Författare :Joakim Sandstedt; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Cardiac progenitor cells; heart; C-kit; Side Population; Stage Specific Embryonic Antigens; FACS;

    Sammanfattning : Traditionally, the heart has been regarded as a non-regenerative organ. During the last 10 years, this notion has been challenged. By 14C measurements, it was calculated that at the age of 50, about 45% of all cardiomyocytes had formed after birth. LÄS MER

  5. 4. Vascular targeting for enhanced cancer immunotherapy

    Författare :Maria Georganaki; Anna Dimberg; Sara Mangsbo; Lena Claesson-Welsh; Wolf Hervé Fridman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer immunotherapy; tumor vasculature; endothelial activation; IDO1; ELTD1; tertiary lymphoid organ; Biologi; Biology;

    Sammanfattning : Induced angiogenesis and chronic inflammation are major components of tumor immunosuppression. The scope of this thesis is to understand the role of the vasculature in anti-tumor immunity and thereby to improve cancer immunotherapy. LÄS MER

  7. 5. Microscopy-based single-cell in vitro assays for NK cell function in 2-D and 3-D

    Författare :Per Erik Olofsson; Björn Önfelt; Khakoo Salim; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biological Physics; Biologisk fysik;

    Sammanfattning : Natural killer (NK) cells are effector cells of the innate immune system that are responsible for mediating cellular cytotoxicity against virally infected or neoplastically transformed cells. NK cell subsets are defined by their expression of certain cell-surface markers, and are usually related to activation and developmental status. LÄS MER