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Visar resultat 1 - 5 av 377 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Cellular transport and secretion of the cyanobacterial neurotoxin BMAA into milk and egg : Implications for developmental neurotoxicity

    Författare :Marie Andersson; Ingvar Brandt; Cynthia de Wit; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; BMAA; beta-N-methylamino-L-alanine; milk; secretion; amino acid transporter; autoradiography; metabolism; Biologi med inriktning mot ekotoxikologi; Biology with specialization in Environmental Toxicology;

    Sammanfattning : The cyanobacterial amino acid β-N-methylamino-L-alanine (BMAA) is a neurotoxin implicated in the etiology of neurodegenerative diseases. Cyanobacteria are cosmopolitan organisms present in various environments. LÄS MER

  2. 2. Single-cell RNA sequencing as a tool to study panarthropod evolution

    Författare :Brenda Irene Medina Jimenez; Ralf Janssen; Graham Budd; Tatjana Haitina; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Single-cell RNA sequencing; EvoDevo; gene expression; tissue dissociation; cell capture; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution;

    Sammanfattning : Panarthropoda is a monophyletic group comprised of arthropods and lobopods, molting animals with a segmented body, paired appendages, dorsal brain, and ventral nerve cords. Evolutionary Developmental Biology (EvoDevo) is an interdisciplinary field that seeks to understand how changes in development form the basis for variations in morphology and phenotypic evolution, including the genetic network underlying these processes. LÄS MER

  3. 3. Long Noncoding RNA Mediated Regulation of Imprinted Genes

    Författare :Faizaan Mohammad; Chandrasekhar Kanduri; Kristian Helin; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Genomic imprinting; noncoding RNA; epigenetics; chromatin; DNA methylation; Developmental biology; Utvecklingsbiologi; Molecular biology; Molekylärbiologi; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Sammanfattning : Genomic imprinting is an epigenetic phenomenon that causes a subset of mammalian genes to be expressed from only one allele in a parent-of-origin manner. The defects in the imprinting regulation result in disorders that affect development, growth and metabolism. LÄS MER

  4. 4. Long bone growth and evolution revealed by three-dimensional imaging

    Författare :Jordi Estefa; Sophie Sanchez; Per Ahlberg; Holly Woodward; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; 3D histology; hematopoiesis; humerus; tetrapods; Biologi; Biology;

    Sammanfattning : Propagation phase-contrast synchrotron radiation microtomography is a non-destructive method used for studying histology in three dimensions (3D). Using it, the 3D organization of the diaphyseal cortical vascularization in the humerus of two seymouriamorphs was analyzed in this thesis. LÄS MER

  5. 5. Characterization of New Players in Planar Polarity Establishment in Arabidopsis

    Författare :Stefano Pietra; Markus Grebe; Niko Geldner; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; SABRE; planar polarity; CLASP; cell division orientation; microtubule cytoskeleton; actin; AIP1; patterning; Developmental Biology; miljömedicinsk utvecklingsbiologi;

    Sammanfattning : Coordinated polarity and differentiation of cells in the plane of a tissue layer are essential to the development of multicellular organisms. Arabidopsis thaliana root hairs and trichomes provide model systems to study the pathways that control planar polarity and cell fate specification in plants. LÄS MER