Sökning: "Development into adulthood"

Visar resultat 21 - 25 av 82 avhandlingar innehållade orden Development into adulthood.

  1. 21. The role of epigenetics in multiple sclerosis development, progression and treatment

    Författare :Ewoud Ewing; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The overall aim of this thesis was to determine epigenetic changes in peripheral immune cells from Multiple Sclerosis (MS) patients. MS is a chronic inflammatory neurodegenerative disease, which initially presents itself during young adulthood. LÄS MER

  3. 22. Epigenetic dysregulation in relation to psychiatric traits in adolescence and adulthood

    Författare :Adrian Desai Boström; Helgi B. Schiöth; Daniel Nätt; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; methylome-wide; DNA methylation; hypersexual disorder; microRNA; oxytocin signaling; psychiatry; hsa-miR-4456; microRNA-4456; MIR4456; epigenetic dysregulation; microRNA expression; gene target prediction; epigenetics; suicide; suicide attempt; HPA axis; CRH gene; Epigenetics; Methylation; Adolescent depression; MIR4646; methylome-wide association study; Omega-3; mQTL analysis; GAD1; HDAC3; DAWBA;

    Sammanfattning : Epigenetics has evolved into a key research focus in the field of psychiatry. DNA methylation is the most researched epigenetic mechanism. In paper I-III, 130 and 93 adolescents were randomly recruited at two separate intervals. LÄS MER

  4. 23. Effect of growth and development on tissue vulnerability : a study on the perinatal rat kidney

    Författare :Eva Serlachius; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :apoptosis; development; DNA synthesis; growth; kidney; ontogeny; PKC; proximal tubular cells; pyelonephritis; rat; sodium; sodium deficiency;

    Sammanfattning : The infant is more vulnerable than older children and adults to pathological processes, such as metabolic disturbances and kidney infection. We have speculated that the vulnerability of the infant kidney may be related to the fact that the kidney at this time is undergoing rapid growth and development. LÄS MER

  5. 24. Long-Term Outcomes of Bullying Victimization With a Specific Focus on Emerging Adulthood and Resilience

    Författare :Johan Lidberg; Göteborgs universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES;

    Sammanfattning : ENGELSK SAMMANFATTNING: Bullying victimization in school is not only an experience at the time of victimization; the impact of these experiences has been found to be connected to long-term outcomes well into adulthood. The overall aim of this licentiate thesis is to broaden the understanding of long-term outcomes from experiencing bullying victimization in school, related to the developmental period of emerging adulthood and how it can be understood in terms of resilience. LÄS MER

  7. 25. Implementing new genomic tools to study ventral midbrain development and injury response in the newt Pleurodeles waltl

    Författare :Zeyu Yao; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Mammals have a poor ability to regenerate organs or tissues. In particular, brain neurons do not regenerate after damage. A good example of this limitation is the irreversible degeneration of midbrain dopaminergic neurons in Parkinson’s disease (PD). Several strategies are being developed to treat PD. LÄS MER