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  1. 1. Studies on the assembly of cytosolic lipid droplets. Importance of Phospholipase D and ADRP in the process

    Författare :Denis Marchesan; Göteborgs universitet; []
    Nyckelord :Lipid droplets; triglycerides; caveolin; Phospholipase D PLD ; adipocyte differentiation related protein ADRP ; EGCG;

    Sammanfattning : The storage of triglycerides in cells such as adipocytes, liver or muscle cells is of great physiological importance, having implications for our most important metabolic diseases such as obesity, the metabolic syndrome and type II diabetes. A common denominator in these diseases is the insulin resistance, which is also highly related to the production of atherogenic lipoproteins and the development of atherosclerosis and consequently cardio-vascular diseases. LÄS MER