Sökning: "Dendritic cells"

Visar resultat 11 - 15 av 385 avhandlingar innehållade orden Dendritic cells.

  1. 11. Presentation of Salmonella antigens by dendritic cells

    Författare :Ulf Yrlid; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; Immunology; antigen processing and presentation; Dendritic cells; Salmonella; transplantation; Immunologi; serologi;

    Sammanfattning : This study investigates the interaction between dendritic cells (DC) and the Gram negative intracellular bacterium Salmonella typhimurium. Using in vitro and in vivo approaches, the capacity of DC to directly and indirectly present antigens from Salmonella-infected cells, cytokine production by infected DC, and activation of bacteria-specific T cells was analyzed. LÄS MER

  2. 12. Regulatory properties of dendritic cells and B cells in adaptive immunity

    Författare :Bengt Johansson Lindbom; Adaptivt immunförsvar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; transplantation; Immunologi; serologi; Immunology; Cellular differentiation; Cytokines; Dendritic cells; B lymphocytes; T lymphocytes;

    Sammanfattning : This thesis is based upon four original papers in which human dendritic cells (DCs) and B cells have been analyzed in terms of how they influence the character of adaptive immune responses. DCs isolated from human tonsils were found to possess a capacity to directly regulate proliferation, isotype switching, and antibody production in B cells. LÄS MER

  3. 13. Subsets of Human Dendritic Cells and their Role in Allergy

    Författare :Kristina Lundberg; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allergy; Dendritic cells; histamine; antibody mediated allergen-presentation; Dendritic cell subsets;

    Sammanfattning : The immune system has evolved to protect the human body against harmful invaders. At the same time, development of tolerance against self-derived and innocuous foreign antigens is of vital importance in order to avoid detrimental immune disorders. In allergic conditions, hypersensitivity is developed against harmless antigens, such as pollen. LÄS MER

  4. 14. Immunity to Rotavirus infection across ages

    Författare :Konjit Getachew Muleta; Virusrekognition; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rotavirus; B cells; T cells; Dendritic cells; Mesenteric Lymph Node; CD8 T cells; Maternal protection; IgA; Neonates; Small Inestinal lamina propria; IFNAR signaling;

    Sammanfattning : Rotavirus (RV) is a double-stranded RNA virus that mainly affects young children under the age of five years. It is one of the leading causes of dehydrating gastroenteritis. Every year, about 200,000 child deaths occur due to RVinfection. Vaccines exist and are in use worldwide. LÄS MER

  5. 15. Potential immunoregulatory role of T and dendritic cells in cancer : Investigations based on transcriptional analysis

    Författare :Milad Abolhalaj; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dendritic cells; T cells; head and neck cancer; acute myeloid leukemia; bladder cancer; T cell exhaustion;

    Sammanfattning : Cancer is a complex disease with various genetic and epigenetic driving factors. Cancer cells form a favored microenvironment to sustain their uncontrolled behavior leading to abnormal growth. With standard treatment including chemotherapy, relapse risk is high due to the resistance that cancer cells can develop against chemotherapy agents. LÄS MER