Sökning: "Dendritic cell subsets"

Visar resultat 1 - 5 av 44 avhandlingar innehållade orden Dendritic cell subsets.

  1. 1. Generating Dendritic Cells by Direct Cell Reprogramming. Merging cellular reprogramming with immunology towards the development of novel cancer immunotherapies

    Författare :Fábio Fiúza Rosa; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dendritic Cell; Direct Cell Reprogramming; Single-cell analysis; Immunotherapy;

    Sammanfattning : Cell fate reprogramming towards pluripotency or alternative somatic cell-types has highlighted the plasticity of adult somatic cells, providing new technologies to generate desired cell types for tissue repair or for disease modeling. There is momentum to bring these concepts to immunology by specifying unique immune cellular identities that set in motion immune responses. LÄS MER

  3. 2. Subsets of Human Dendritic Cells and their Role in Allergy

    Författare :Kristina Lundberg; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allergy; Dendritic cells; histamine; antibody mediated allergen-presentation; Dendritic cell subsets;

    Sammanfattning : The immune system has evolved to protect the human body against harmful invaders. At the same time, development of tolerance against self-derived and innocuous foreign antigens is of vital importance in order to avoid detrimental immune disorders. In allergic conditions, hypersensitivity is developed against harmless antigens, such as pollen. LÄS MER

  4. 3. Regulation of B cell function by plasmacytoid dendritic cells

    Författare :Cornelia Gujer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Dendritic cell;

    Sammanfattning : Dendritic cells (DCs) are early sentinels of pathogen exposure and central in the initiation and orchestration of adaptive immune responses. Apart from the prominent role of DCs in the activation of T cells, DCs have been shown to influence humoral B cell mediated responses. LÄS MER

  5. 4. Mechanisms of dendritic cell maturation induced by intracellular bacteria infection

    Författare :Miguel A. Tam; Göteborgs universitet; []
    Nyckelord :Listeria; Salmonella; dendritic cells; maturation; MyD88; IFN-? ?;

    Sammanfattning : Dendritic cells (DCs) are essential for the development of an immune response against pathogens such as Listeria monocytogenes and Salmonella typhimurium. This is mostly because of their unique capacity to stimulate naïve T cells. LÄS MER

  7. 5. Oxidant-induced cell death in lymphocytes: mechanisms of induction and resistance

    Författare :Fredrik Bergh Thorén; Göteborgs universitet; []
    Nyckelord :reactive oxygen species; cell death; apoptosis; poly ADP-ribose polymerase-1; apoptosis-inducing factor; natural killer cells; phagocytes; dendritic cells;

    Sammanfattning : Reactive oxygen species (oxidants, oxygen radicals) produced by the phagocytic NADPH oxidase have pivotal roles in immunity. Patients lacking a functional NADPH oxidase suffer from chronic granulomatous disease, which is characterized by recurring bacterial infections and thus manifesting the importance of reactive oxygen species in host defense against bacteria. LÄS MER